ID DDRGK_ARATH Reviewed; 298 AA.
AC Q94C53; Q8LAA5; Q9T046;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 24-JAN-2024, entry version 120.
DE RecName: Full=DDRGK domain-containing protein 1;
DE Flags: Precursor;
GN OrderedLocusNames=At4g27120; ORFNames=T24A18.70;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DDRGK1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB38842.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79567.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL035680; CAB38842.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161566; CAB79567.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE85303.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE85304.1; -; Genomic_DNA.
DR EMBL; AY035174; AAK59678.1; -; mRNA.
DR EMBL; AY113927; AAM44975.1; -; mRNA.
DR EMBL; AY087946; AAM65494.1; -; mRNA.
DR PIR; T06042; T06042.
DR RefSeq; NP_567767.1; NM_118846.4.
DR RefSeq; NP_849456.1; NM_179125.4.
DR AlphaFoldDB; Q94C53; -.
DR SMR; Q94C53; -.
DR STRING; 3702.Q94C53; -.
DR iPTMnet; Q94C53; -.
DR PaxDb; 3702-AT4G27120-1; -.
DR ProteomicsDB; 224127; -.
DR EnsemblPlants; AT4G27120.1; AT4G27120.1; AT4G27120.
DR EnsemblPlants; AT4G27120.2; AT4G27120.2; AT4G27120.
DR GeneID; 828820; -.
DR Gramene; AT4G27120.1; AT4G27120.1; AT4G27120.
DR Gramene; AT4G27120.2; AT4G27120.2; AT4G27120.
DR KEGG; ath:AT4G27120; -.
DR Araport; AT4G27120; -.
DR TAIR; AT4G27120; -.
DR eggNOG; KOG3054; Eukaryota.
DR HOGENOM; CLU_059562_2_0_1; -.
DR InParanoid; Q94C53; -.
DR OMA; QEFIQYI; -.
DR OrthoDB; 197573at2759; -.
DR PhylomeDB; Q94C53; -.
DR PRO; PR:Q94C53; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q94C53; baseline and differential.
DR Genevisible; Q94C53; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019153; DDRGK_dom-contain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR48176; DDRGK DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR48176:SF1; DDRGK DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF09756; DDRGK; 1.
DR SMART; SM01128; DDRGK; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..298
FT /note="DDRGK domain-containing protein 1"
FT /id="PRO_0000391870"
FT REGION 31..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 298 AA; 34019 MW; CCFBDAAEFC144E3D CRC64;
MEEIFALIVS MILIVAVIPL FFWKRRRDAR SREEVAEPPQ VQPRENVARA GGGRRMRRRP
AASGASSSTS NVQENGSGSE DEDEDEAGGT QARASKKKEK KRQEREAQRQ AEEATRESRN
TKQDWYAEMR RKKDEEREAE ELKLEEEEKA RQAKEEEAAA LEFDKWKGEF SVDAEGTTEE
VQGGNQDLLS EFVEYIKKQK CVPLEDLAAE FHLRTQECIN RIASLESIGR LSGVMDDRGK
YIYISMEEMN AVADYIKRQG RVSISHLASK SNQFIDLEPK VQHQLTEEIS GMEEISVS
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