GenomeNet

Database: UniProt
Entry: DENR_NEUCR
LinkDB: DENR_NEUCR
Original site: DENR_NEUCR 
ID   DENR_NEUCR              Reviewed;         187 AA.
AC   Q9P3T4;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   24-JAN-2024, entry version 106.
DE   RecName: Full=Translation machinery-associated protein 22;
GN   Name=tma-22; ORFNames=B24P7.010, NCU02984;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12655011; DOI=10.1093/nar/gkg293;
RA   Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA   Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT   "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT   genome sequence.";
RL   Nucleic Acids Res. 31:1944-1954(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC   -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL389890; CAB97266.1; -; Genomic_DNA.
DR   EMBL; CM002236; EAA36134.1; -; Genomic_DNA.
DR   PIR; T50946; T50946.
DR   RefSeq; XP_965370.1; XM_960277.3.
DR   AlphaFoldDB; Q9P3T4; -.
DR   SMR; Q9P3T4; -.
DR   STRING; 367110.Q9P3T4; -.
DR   PaxDb; 5141-EFNCRP00000002471; -.
DR   EnsemblFungi; EAA36134; EAA36134; NCU02984.
DR   GeneID; 3881495; -.
DR   KEGG; ncr:NCU02984; -.
DR   VEuPathDB; FungiDB:NCU02984; -.
DR   HOGENOM; CLU_073511_0_1_1; -.
DR   InParanoid; Q9P3T4; -.
DR   OMA; EVFEIDM; -.
DR   OrthoDB; 130735at2759; -.
DR   Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0002188; P:translation reinitiation; IBA:GO_Central.
DR   CDD; cd11607; DENR_C; 1.
DR   Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR   InterPro; IPR046447; DENR_C.
DR   InterPro; IPR005873; DENR_eukaryotes.
DR   InterPro; IPR048517; DENR_N.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   NCBIfam; TIGR01159; DRP1; 1.
DR   PANTHER; PTHR12789:SF0; DENSITY-REGULATED PROTEIN; 1.
DR   PANTHER; PTHR12789; DENSITY-REGULATED PROTEIN HOMOLOG; 1.
DR   Pfam; PF21023; DENR_N; 1.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; eIF1-like; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..187
FT                   /note="Translation machinery-associated protein 22"
FT                   /id="PRO_0000320447"
FT   DOMAIN          94..165
FT                   /note="SUI1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
SQ   SEQUENCE   187 AA;  20756 MW;  27F5AD68D6127EAB CRC64;
     MTALTGRPVV YCGVCSLPPE YCEYGGTVKK CQQWLEKNQP TMYSRIWSPE VLEAEMASLS
     VEAQERAMKD AKKKAAKAEA AEQKQADKRA NSVVTIKRIE RNKRKYVTSV SGLEAFGLEL
     KKVAKDFGKK FATGSSVTKV PSGGEEIVVQ GDVSGEIEEF ILEKYKEVPE DNIELVEDKK
     KKKGEGN
//
DBGET integrated database retrieval system