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Database: UniProt
Entry: DNAA_GEOBB
LinkDB: DNAA_GEOBB
Original site: DNAA_GEOBB 
ID   DNAA_GEOBB              Reviewed;         458 AA.
AC   B5E7P6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   16-JAN-2019, entry version 64.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Gbem_0001;
OS   Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=404380;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bem / ATCC BAA-1014 / DSM 16622;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Lykidis A., Lovley D., Richardson P.;
RT   "Complete sequence of Geobacter bemidjiensis BEM.";
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001124; ACH37034.1; -; Genomic_DNA.
DR   RefSeq; WP_012528443.1; NC_011146.1.
DR   ProteinModelPortal; B5E7P6; -.
DR   SMR; B5E7P6; -.
DR   STRING; 404380.Gbem_0001; -.
DR   EnsemblBacteria; ACH37034; ACH37034; Gbem_0001.
DR   KEGG; gbm:Gbem_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; FPAFKIV; -.
DR   OrthoDB; 219876at2; -.
DR   BioCyc; GBEM404380:G1GCH-1-MONOMER; -.
DR   Proteomes; UP000008825; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    458       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000121983.
FT   NP_BIND     163    170       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   458 AA;  52407 MW;  BF9EDB86586CEA85 CRC64;
     MENIWLEAQT NLKQVLTEQT YSTWIDPLKF LGATVDTIVL EVPSSFFQKW VTDKYLAMIK
     EAISAVNGKS YQIEFHVAEE KPEAAHEAKP EKEAKPAREK ERDKDKEKEK DREKEKKELV
     PNLNPKYTFE SFVSGPSNQF AYAASQAVAN KPATNYNPLF IYGGVGLGKT HLVNAIGNHI
     LAKNPKAKIC YYSSEKFMNE MINSLRYKKM DEFRNKFRKM DLLLIDDIQF MAGKEATQEE
     FFHTFNALYE SHKQIVVTSD KFPKDIPGLE ERLRSRFEWG LIADIQPPGV ETKVAILKKK
     SDMHAVNLPD DVALFLAEGA NSNIRELEGM LIRLEAFASL TGQEITLSMA REVMKDIIVE
     KTRDITVEMI QKTVAEHFRI KVSELKSDKR IKTLVVPRQI AIYICRELTK ASYPEIGEKF
     GGKDHSTIIH SVKKIEKQIA GDDEFKATVE DIRKKLFT
//
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