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Database: UniProt
Entry: DNAA_VIBVY
LinkDB: DNAA_VIBVY
Original site: DNAA_VIBVY 
ID   DNAA_VIBVY              Reviewed;         468 AA.
AC   Q7MQJ7;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   16-JAN-2019, entry version 97.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=VV0011;
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=196600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016;
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C.,
RA   Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L.,
RA   Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine
RT   pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; BA000037; BAC92775.1; -; Genomic_DNA.
DR   RefSeq; WP_011149053.1; NC_005139.1.
DR   ProteinModelPortal; Q7MQJ7; -.
DR   SMR; Q7MQJ7; -.
DR   EnsemblBacteria; BAC92775; BAC92775; BAC92775.
DR   GeneID; 2622759; -.
DR   KEGG; vvy:VV0011; -.
DR   PATRIC; fig|196600.6.peg.65; -.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000002675; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    468       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114300.
FT   NP_BIND     173    180       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   468 AA;  53116 MW;  462D662ADED0CBFF CRC64;
     MSSSLWLQCM QRLQEELPAT EFSMWVRPLQ AELNDNTLTL FAPNRFVLDW VRDKYLNSIN
     RLLQEYCGHD IPNLRFEVGS RPMAAPKPAP TRTPADVAAE SSAPAQLQAR KPVHKTWDDD
     AQAIADINHR SNVNPKHKFN NFVEGKSNQL GLAAARQVAD NPGGAYNPLF LYGGTGLGKT
     HLLHAVGNAI VDNKPNAKVV YMHSERFVQD MVKALQNNAI EEFKRYYRSV DALLIDDIQF
     FANKERSQEE FFHTFNALLE GNQQIILTSD RYPKEISGVE DRLKSRFGWG LTVAIEPPEL
     ETRVAILMKK AEDHQIHLAD EVAFFIAKRL RSNVRELEGA LNRVIANANF TGRPITIDFV
     REALRDLLAL QEKLVTIDNI QKTVAEYYKI KVADLLSKRR SRSVARPRQL AMALAKELTN
     HSLPEIGDAF GGRDHTTVLH ACRKIEQLRE ESHDIKEDYS NLIRTLSS
//
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