ID DNAT_SHIFL Reviewed; 179 AA.
AC P0A8J3; P07904;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 24-JAN-2024, entry version 93.
DE RecName: Full=Primosomal protein 1;
DE AltName: Full=Primosomal protein I;
GN Name=dnaT; OrderedLocusNames=SF4393, S4663;
OS Shigella flexneri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: This protein is required for primosome-dependent normal DNA
CC replication; it is also involved in inducing stable DNA replication
CC during SOS response. It forms, in concert with DnaB protein and other
CC prepriming proteins DnaC, N, N', N'' a prepriming protein complex on
CC the specific site of the template DNA recognized by protein N' (By
CC similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DnaT family. {ECO:0000305}.
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DR EMBL; AE005674; AAN45808.2; -; Genomic_DNA.
DR EMBL; AE014073; AAP19586.1; -; Genomic_DNA.
DR RefSeq; NP_710101.2; NC_004337.2.
DR RefSeq; WP_000098818.1; NZ_WPGW01000045.1.
DR AlphaFoldDB; P0A8J3; -.
DR SMR; P0A8J3; -.
DR STRING; 198214.SF4393; -.
DR PaxDb; 198214-SF4393; -.
DR GeneID; 1026738; -.
DR GeneID; 75202955; -.
DR KEGG; sfl:SF4393; -.
DR KEGG; sfx:S4663; -.
DR PATRIC; fig|198214.7.peg.5179; -.
DR HOGENOM; CLU_1501592_0_0_6; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.8.1180; -; 1.
DR HAMAP; MF_01061; DnaT; 1.
DR InterPro; IPR020917; DnaT.
DR InterPro; IPR040480; DnaT_DNA_bind.
DR Pfam; PF17948; DnaT; 1.
PE 3: Inferred from homology;
KW DNA replication; Primosome; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..179
FT /note="Primosomal protein 1"
FT /id="PRO_0000199875"
FT REGION 156..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 179 AA; 19455 MW; 8DE048A3B2A6235B CRC64;
MSSRVLTPDV VGIDALVHDH QTVLAKAEGG VVAVFANNAP AFYAVTPARL AELLALEEKL
ARPGSDVALD DQLYQEPQAA PVAVPMGKFA MYPDWQPDAD FIRLAALWGV ALREPVTTEE
LASFIAYWQA EGKVFHHVQW QQKLARSLQI GRASNGGLPK RDVNTVSEPD SQIPPGFRG
//
