ID DR102_ARATH Reviewed; 310 AA.
AC Q05212; Q941E8;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2007, sequence version 2.
DT 27-MAR-2024, entry version 133.
DE RecName: Full=DNA damage-repair/toleration protein DRT102;
GN Name=DRT102; OrderedLocusNames=At3g04880; ORFNames=T9J14.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 54-310.
RC STRAIN=cv. Columbia;
RX PubMed=8329681; DOI=10.1007/bf00015972;
RA Pang Q., Hays J.B., Rajagopal I., Schaefer T.S.;
RT "Selection of Arabidopsis cDNAs that partially correct phenotypes of
RT Escherichia coli DNA-damage-sensitive mutants and analysis of two plant
RT cDNAs that appear to express UV-specific dark repair activities.";
RL Plant Mol. Biol. 22:411-426(1993).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA72353.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAG51425.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC009465; AAG51425.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE74150.1; -; Genomic_DNA.
DR EMBL; AY052206; AAK97677.1; -; mRNA.
DR EMBL; AY143862; AAN28801.1; -; mRNA.
DR EMBL; L11368; AAA72353.1; ALT_INIT; mRNA.
DR PIR; S35271; S35271.
DR RefSeq; NP_566241.1; NM_111360.2.
DR AlphaFoldDB; Q05212; -.
DR SMR; Q05212; -.
DR STRING; 3702.Q05212; -.
DR iPTMnet; Q05212; -.
DR PaxDb; 3702-AT3G04880-1; -.
DR ProteomicsDB; 241255; -.
DR EnsemblPlants; AT3G04880.1; AT3G04880.1; AT3G04880.
DR GeneID; 819648; -.
DR Gramene; AT3G04880.1; AT3G04880.1; AT3G04880.
DR KEGG; ath:AT3G04880; -.
DR Araport; AT3G04880; -.
DR TAIR; AT3G04880; DRT102.
DR eggNOG; ENOG502QS8W; Eukaryota.
DR HOGENOM; CLU_053058_0_0_1; -.
DR InParanoid; Q05212; -.
DR OMA; FIKWDGH; -.
DR OrthoDB; 1472732at2759; -.
DR PhylomeDB; Q05212; -.
DR PRO; PR:Q05212; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q05212; baseline and differential.
DR Genevisible; Q05212; AT.
DR GO; GO:0005737; C:cytoplasm; HDA:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 3.40.1400.10; Sugar-phosphate isomerase, RpiB/LacA/LacB; 1.
DR InterPro; IPR013096; Cupin_2.
DR InterPro; IPR012100; DRT102.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR InterPro; IPR003500; RpiB_LacA_LacB.
DR InterPro; IPR036569; RpiB_LacA_LacB_sf.
DR PANTHER; PTHR30345:SF0; DNA DAMAGE-REPAIR_TOLERATION PROTEIN DRT102; 1.
DR PANTHER; PTHR30345; RIBOSE-5-PHOSPHATE ISOMERASE B; 1.
DR Pfam; PF07883; Cupin_2; 1.
DR Pfam; PF02502; LacAB_rpiB; 1.
DR PIRSF; PIRSF011609; DRT102; 1.
DR SUPFAM; SSF89623; Ribose/Galactose isomerase RpiB/AlsB; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 1: Evidence at protein level;
KW Acetylation; DNA damage; DNA repair; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..310
FT /note="DNA damage-repair/toleration protein DRT102"
FT /id="PRO_0000079998"
FT DOMAIN 219..282
FT /note="Cupin type-2"
FT /evidence="ECO:0000255"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 310 AA; 33233 MW; 47520159E2687616 CRC64;
MAGAVSAVDQ PLKIITGADD FGASLKDAMV THLRSLGIDV EDTGVSSYYS AGSEVGRRVS
ASSSSEVRGL VCCGTGVGVA MFANKFPGVY AATCLSVEDA VNARSISNCN VLAFSGIKTS
PETALEIFDA WIKTPFKSPC PASGSEPWSS VISSFLDNSL SEMSQIGKST AGDSTTKKID
ETTASCVICC LAKNREFTPV DIMPGGSMKI VRETPTSAIV RFKAGSVEPA HHHTFGHDLV
VIKGKKSVWN LSKKERADLV DGDYLFTPAG DVHRVKYHED TEFFITWDGH WDIFLDEDLE
TAKKAIEEEA
//
