GenomeNet

Database: UniProt
Entry: E0AHC2_CAEEL
LinkDB: E0AHC2_CAEEL
Original site: E0AHC2_CAEEL 
ID   E0AHC2_CAEEL            Unreviewed;       401 AA.
AC   E0AHC2;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   11-DEC-2019, entry version 79.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBW44362.1};
GN   Name=svh-5 {ECO:0000313|EMBL:CBW44362.1,
GN   ECO:0000313|WormBase:C33A11.4b};
GN   Synonyms=tag-97 {ECO:0000313|WormBase:C33A11.4b};
GN   ORFNames=C33A11.4 {ECO:0000313|WormBase:C33A11.4b}, CELE_C33A11.4
GN   {ECO:0000313|EMBL:CBW44362.1};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000313|EMBL:CBW44362.1, ECO:0000313|Proteomes:UP000001940};
RN   [1] {ECO:0000313|EMBL:CBW44362.1, ECO:0000313|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000313|EMBL:CBW44362.1,
RC   ECO:0000313|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RA   Sulson J.E., Waterston R.;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX284606; CBW44362.1; -; Genomic_DNA.
DR   RefSeq; NP_001257262.1; NM_001270333.1.
DR   SMR; E0AHC2; -.
DR   EnsemblMetazoa; C33A11.4b.1; C33A11.4b.1; WBGene00006462.
DR   CTD; 181627; -.
DR   WormBase; C33A11.4b; CE45227; WBGene00006462; svh-5.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   GeneTree; ENSGT00940000169058; -.
DR   OrthoDB; 837296at2759; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00006462; Expressed in 4 organ(s), highest expression level in multi-cellular organism.
DR   ExpressionAtlas; E0AHC2; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT   DOMAIN          26..113
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          302..389
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          272..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..287
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   401 AA;  45306 MW;  1E73CE8F1F1AA006 CRC64;
     MCIPKLLQEI SNNKVLRTRM NNTAYKPIPN NEKVDLARFR VKDPNEWLVD DVVAWMLDVA
     KRHNIPFEEM NMHKFAMLSG QEMLTMSERC FIERDPVFGN LIFNEFRKTL ENSEDTTLDT
     VIGPFVDDEI ATTSAPPTIV DMTSLGLQPM ISSITCTIQP PLQHPTPHLA PLPVMQHQLN
     NLSSLTQVLS QQTFNTTILT PQQTANAVQS LNQSLASSIA AGLTSSLSPL GVNYQLSSRL
     NPASPLLSAP IQPKLSPMLK YSCTINTEYE VPEERSAESS DLKIKKNKDG KPRKRSQHTK
     GNKLWEFIRD ALKDPSTCPS VVRWEDPIEG VFRIVESEKL ARLWGARKNN EKMTYEKLSR
     AMRTYYEKQI LVPVPKTGLY PKKLVYKFGP GAHGWENVKG I
//
DBGET integrated database retrieval system