ID   E0CQW4_VITVI            Unreviewed;       887 AA.
AC   E0CQW4;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   OrderedLocusNames=VIT_18s0001g00910 {ECO:0000313|EMBL:CBI18918.3};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI18918.3, ECO:0000313|Proteomes:UP000009183};
RN   [1] {ECO:0000313|Proteomes:UP000009183}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX   PubMed=17721507; DOI=10.1038/nature06148;
RG   The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA   Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA   Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA   Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA   Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA   Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA   Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA   Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA   Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA   Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA   Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA   Wincker P.;
RT   "The grapevine genome sequence suggests ancestral hexaploidization in major
RT   angiosperm phyla.";
RL   Nature 449:463-467(2007).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR   EMBL; FN595227; CBI18918.3; -; Genomic_DNA.
DR   RefSeq; XP_010664130.1; XM_010665828.2.
DR   AlphaFoldDB; E0CQW4; -.
DR   STRING; 29760.E0CQW4; -.
DR   PaxDb; 29760-VIT_18s0001g00910-t01; -.
DR   EnsemblPlants; Vitvi18g00171_t001; Vitvi18g00171_P001; Vitvi18g00171.
DR   GeneID; 100245339; -.
DR   Gramene; Vitvi18g00171_t001; Vitvi18g00171_P001; Vitvi18g00171.
DR   KEGG; vvi:100245339; -.
DR   eggNOG; KOG2023; Eukaryota.
DR   HOGENOM; CLU_008136_1_0_1; -.
DR   InParanoid; E0CQW4; -.
DR   OMA; CAYGRYQ; -.
DR   OrthoDB; 276400at2759; -.
DR   Proteomes; UP000009183; Chromosome 18.
DR   ExpressionAtlas; E0CQW4; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009183}.
FT   DOMAIN          30..98
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          316..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..348
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   887 AA;  98646 MW;  F52F842126903569 CRC64;
     MAWRPQEEGL GEICGLLEQH ISPTSDKSVI WKQLQHYKQF SDFNNYLAFI FAHAEGKSVE
     IRQAAGLLLK NNLRSSFRTL DPAHQQYIKS ELLPCLGAAD KHIRSTVGTI ITVIVQQGRI
     FGWPELLQAL VHCLDSNDLN LMEGALAALL KICEDIPQEL DSEIPGLTER PIDAFLPRLF
     QLFKSPHVSI RKLSLGSINQ FIILMPTALF MSMDQCLQGL FVLAHDPIAE IRKLVCAAFV
     QLVEVQPAVL EPHMRNIIEY MLQANRDADD EVALESCEFW STYCEAQLDP ELLREFLPHL
     IPVLLSNMAY AEDDESLADA EEDESIPDRD QDLKPRFHSS RSHGLDDMKD DDDEAVNIWN
     LRKCSAAGLD ILSDVFGDEI LPTLMPLVQA KLSTSDARSW KEREAAVLAL GAIAEGCVRG
     LFPHLAEIVA FLIPLLDDKF PLIRSITCWT LSRFSKFIVQ GVGHQKGYDQ FNRVLVGLLQ
     RVLDTNKRVQ EAACSAFATL EEEAAEELTP HVAIILQHLL CAFGRYQKRN LRILYDAIGT
     LADAVGGELN QSRYLDILMP PLIAKWQLVS NSDKDLFPLL ECFTSIAQAL GTGFSQFAEP
     VFQRCISIIQ SQLLAKASVD PLSAAVQYDK EFIVCSLDLL SGLAEGLGSG IESLAAQSNL
     RDLLLQCCMD DASDVCQSAL ALLGDLARAC PVYLHPRLSE FLNVAARRLN PPEVKETFSV
     ANNACWAIGE LAVKAHKEVS PIVMTVVSCL APILQQAEGF NKSLVENSAI TLGRLAWVCP
     EIVALHMEHF MQSWCTALST IRDDIEKEDA FRGLCATVRA NPSGALSSLV HMCKAIASWH
     HIRSEDLHND ICQVLKGFKQ MLNNGAWEQC MSALEPPEKE KLLNYLI
//