ID E0CX87_MOUSE Unreviewed; 219 AA.
AC E0CX87;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Zinc finger with KRAB and SCAN domains 5 {ECO:0000313|Ensembl:ENSMUSP00000124838.2};
GN Name=Zkscan5 {ECO:0000313|Ensembl:ENSMUSP00000124838.2,
GN ECO:0000313|MGI:MGI:107533};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000124838.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000124838.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124838.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000124838.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124838.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00187}.
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DR AlphaFoldDB; E0CX87; -.
DR SMR; E0CX87; -.
DR Antibodypedia; 30392; 145 antibodies from 21 providers.
DR Ensembl; ENSMUST00000161896.2; ENSMUSP00000124838.2; ENSMUSG00000055991.16.
DR AGR; MGI:107533; -.
DR MGI; MGI:107533; Zkscan5.
DR VEuPathDB; HostDB:ENSMUSG00000055991; -.
DR GeneTree; ENSGT00940000162299; -.
DR HOGENOM; CLU_1261135_0_0_1; -.
DR ChiTaRS; Zkscan5; mouse.
DR Proteomes; UP000000589; Chromosome 5.
DR Bgee; ENSMUSG00000055991; Expressed in secondary oocyte and 240 other cell types or tissues.
DR ExpressionAtlas; E0CX87; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR PANTHER; PTHR45935; PROTEIN ZBED8-RELATED; 1.
DR PANTHER; PTHR45935:SF26; SCAN DOMAIN-CONTAINING PROTEIN SCAND2P-RELATED; 1.
DR Pfam; PF02023; SCAN; 1.
DR SMART; SM00431; SCAN; 1.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 51..132
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT REGION 148..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 219 AA; 25011 MW; C4747BD9BED371A0 CRC64;
MIMTESRAVI HLEPPAETSQ EQADLLIVKV EEEDCSWMQG YNRPVLETFY QRFKHFQYHE
AAGPRDALSQ LRVLCCEWLR PELHTKEQIL ELLVLEQFLT ILPEEFQAWV REHHPESGEE
AVAVIESIQR ELEERRQQLW LLDCHKSRST SSEDGTTRSH AGVLQSPVST CGGPARARVT
ESSGRKCPSC SPGFFRSPEG QPGADRFTPL RWAPEVGEN
//
