ID E0E108_9FIRM Unreviewed; 473 AA.
AC E0E108;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:EFM65396.1};
GN ORFNames=HMPREF0634_0759 {ECO:0000313|EMBL:EFM65396.1};
OS Peptostreptococcus stomatis DSM 17678.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Peptostreptococcus.
OX NCBI_TaxID=596315 {ECO:0000313|EMBL:EFM65396.1, ECO:0000313|Proteomes:UP000003244};
RN [1] {ECO:0000313|EMBL:EFM65396.1, ECO:0000313|Proteomes:UP000003244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17678 {ECO:0000313|EMBL:EFM65396.1,
RC ECO:0000313|Proteomes:UP000003244};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM65396.1}.
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DR EMBL; ADGQ01000002; EFM65396.1; -; Genomic_DNA.
DR RefSeq; WP_007787900.1; NZ_ADGQ01000002.1.
DR AlphaFoldDB; E0E108; -.
DR STRING; 596315.HMPREF0634_0759; -.
DR GeneID; 84799834; -.
DR eggNOG; COG0535; Bacteria.
DR OrthoDB; 9782387at2; -.
DR Proteomes; UP000003244; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21128; SPASM_rSAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43524; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43524:SF1; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003244};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 110..324
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 473 AA; 53943 MW; 7169F97EFCECB4F5 CRC64;
MGIAHSLERA VASKGIEAVI KSLKSKNNDE KEKAMLNLVD IYQKFAGSMF EESTYDTVRE
MIRDKDGKWI NYAYGLLDRV DTNVLKMTAL NLGFTSSYYG KKIINEKRLE HGCNVPWLIL
MDPTSACNLK CKGCWAAEYG HNQSLSFEEL DDIIEQGKKL GIYFYMYTGG EPLMRKKDLI
RLCDKHRDCY FLAFTNGTLI DDDFANEVAR VGNFSVALSI EGFEETNDAR RGKGIYQSTL
KAMDIMKAHG LVYGTSICYT SQNLETVVSD EFMDLLIDKG VMYSWFFNYM PVGNDAVPEL
IPSPEQREYI YHRIREIRAK DGGKPIMLID FQNDGEFIGG CIAGGRNYLH INSAGDVEPC
VFIHYSNANI REKSLLECLK QPIFMEYRAG QPFNDNHLRP CPMLENPELL REMVKRSGAH
STDLISPETV EHLTDKCRPY ADSWKPTADR LWSESLDKKM KANKNISDHK QVI
//
