ID E0E2H9_9FIRM Unreviewed; 358 AA.
AC E0E2H9;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=beta-ketoacyl-[acyl-carrier-protein] synthase III {ECO:0000256|ARBA:ARBA00012333};
DE EC=2.3.1.180 {ECO:0000256|ARBA:ARBA00012333};
GN ORFNames=HMPREF0634_1309 {ECO:0000313|EMBL:EFM64949.1};
OS Peptostreptococcus stomatis DSM 17678.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Peptostreptococcus.
OX NCBI_TaxID=596315 {ECO:0000313|EMBL:EFM64949.1, ECO:0000313|Proteomes:UP000003244};
RN [1] {ECO:0000313|EMBL:EFM64949.1, ECO:0000313|Proteomes:UP000003244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17678 {ECO:0000313|EMBL:EFM64949.1,
RC ECO:0000313|Proteomes:UP000003244};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM64949.1}.
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DR EMBL; ADGQ01000035; EFM64949.1; -; Genomic_DNA.
DR AlphaFoldDB; E0E2H9; -.
DR STRING; 596315.HMPREF0634_1309; -.
DR eggNOG; COG0332; Bacteria.
DR OrthoDB; 9815506at2; -.
DR Proteomes; UP000003244; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0033818; F:beta-ketoacyl-acyl-carrier-protein synthase III activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00830; KAS_III; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR004655; FabH.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR00747; fabH; 1.
DR PANTHER; PTHR43091; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE; 1.
DR PANTHER; PTHR43091:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III 2; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EFM64949.1};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000003244};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFM64949.1}.
FT DOMAIN 106..172
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 242..335
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 358 AA; 39351 MW; A87F85DE4F4F57AE CRC64;
MTINIISTGS YAGEKILDNE YFAKIVDTND EWIQERTGIK TRHICDDITT EEMAARAGES
ALKKLNIDRS KIGLVILATV SSDTKTPASS FTVAGNLGLK GNPICFDLNA ACSGFVYSMA
VARSIMADMN IAYAMIIGAE RLSKFVNWSD RGTCILFGDG AGCAILENSD LADPEVTSSL
DYKLEIEGDY LAGKFDSNRY LTLDSRFSLD EKKYPYIGMN GRQIYKFATD VGVKVIDRLL
GDKGLSKDDI ELIVPHQANK RIIETLAIKS QIPESKWFVN LDKYGNTSAA SIPLALNEVV
EDVLAARNVD QMDGKRILSV AFGGGLSYGG FLLKIRKNKT NKKLIGNQNR HQTVDRNI
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