ID E0NQZ4_9BACT Unreviewed; 587 AA.
AC E0NQZ4;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=AMP-binding enzyme {ECO:0000313|EMBL:EFM02514.1};
DE EC=6.2.1.3 {ECO:0000313|EMBL:EFM02514.1};
GN ORFNames=HMPREF0658_0595 {ECO:0000313|EMBL:EFM02514.1};
OS Hoylesella marshii DSM 16973 = JCM 13450.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=862515 {ECO:0000313|EMBL:EFM02514.1, ECO:0000313|Proteomes:UP000004394};
RN [1] {ECO:0000313|EMBL:EFM02514.1, ECO:0000313|Proteomes:UP000004394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16973 {ECO:0000313|EMBL:EFM02514.1,
RC ECO:0000313|Proteomes:UP000004394};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-
CC CoA + AMP + diphosphate; Xref=Rhea:RHEA:15421, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:57287, ChEBI:CHEBI:57560,
CC ChEBI:CHEBI:83139, ChEBI:CHEBI:456215; EC=6.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00024484};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:15422;
CC Evidence={ECO:0000256|ARBA:ARBA00024484};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM02514.1}.
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DR EMBL; AEEI01000021; EFM02514.1; -; Genomic_DNA.
DR AlphaFoldDB; E0NQZ4; -.
DR STRING; 862515.HMPREF0658_0595; -.
DR eggNOG; COG1022; Bacteria.
DR HOGENOM; CLU_000022_59_9_10; -.
DR BioCyc; PMAR862515-HMP:GMOO-608-MONOMER; -.
DR Proteomes; UP000004394; Unassembled WGS sequence.
DR GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43272:SF83; ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J; 1.
DR PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EFM02514.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004394}.
FT DOMAIN 55..446
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 587 AA; 66446 MW; C905E10930C8EB8D CRC64;
MTLDGLHRAL QNGTNYFEVC NKSIIFAQIF MICAMKTIPS FNAYIEKSIT EHWHLNALTD
YQGATLQYND VARKIEKLHI LFEHSGIVKG DKIALCGRNC AHWGVAFLAT LTYGAIAVPI
LHEFTPDQIH HIVNHSDAKL LFVGDVVATE VDATKMPALE GIVYIPDYSL VISRTDRLTY
AREHLNEIFG KKYPKYFRAE HVKYYREQSP DELALINYTS GTTGFSKGVM IPYRALWSNL
DFAFHVLGDK VHHGDSIISI LPMAHMYGMA FEFLFEFCSG CHIFFLTRIP SPAIIAQAFA
DVRPTIIIAV PLIIEKIIRK KVFPKIQNNK MRLLLGMPVI NKKVNQKICE QVMNAFGGRF
YEIIIGGAAF NQEVEQFLHK IDFPYTVGYG ATECAPIITY ADYQTFVPGS CGRAVIHMEV
KIDSNDPQHV PGEILARGLN VMLGYYKNEE ATREVIDTEG WYHTGDLGQM DEEGNVFIKG
RSKNMLLGSN GQNIYPEEIE DKLNSMALVS ESLVIQEGER LVGLVHPDYD EAKTLGLTVE
DLENVMTQNC RELNAMIPAY CKLSAIKLHE EEFEKTPKKS IKRYLYQ
//
