ID E0NTQ6_9BACT Unreviewed; 451 AA.
AC E0NTQ6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Citrate transporter {ECO:0000313|EMBL:EFM01439.1};
GN Name=nhaD {ECO:0000313|EMBL:EFM01439.1};
GN ORFNames=HMPREF0658_1559 {ECO:0000313|EMBL:EFM01439.1};
OS Hoylesella marshii DSM 16973 = JCM 13450.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=862515 {ECO:0000313|EMBL:EFM01439.1, ECO:0000313|Proteomes:UP000004394};
RN [1] {ECO:0000313|EMBL:EFM01439.1, ECO:0000313|Proteomes:UP000004394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16973 {ECO:0000313|EMBL:EFM01439.1,
RC ECO:0000313|Proteomes:UP000004394};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter
CC family. {ECO:0000256|ARBA:ARBA00025753}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM01439.1}.
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DR EMBL; AEEI01000050; EFM01439.1; -; Genomic_DNA.
DR RefSeq; WP_006949717.1; NZ_GL397214.1.
DR AlphaFoldDB; E0NTQ6; -.
DR STRING; 862515.HMPREF0658_1559; -.
DR eggNOG; COG1055; Bacteria.
DR HOGENOM; CLU_029697_1_0_10; -.
DR OrthoDB; 9772058at2; -.
DR Proteomes; UP000004394; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR045016; NhaD-like.
DR NCBIfam; NF038006; NhaD_1; 1.
DR PANTHER; PTHR43269; SODIUM/PROTON ANTIPORTER 1-RELATED; 1.
DR PANTHER; PTHR43269:SF2; SODIUM_PROTON ANTIPORTER 1-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004394};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 30..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..383
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 451 AA; 48870 MW; E7D4EE247583634C CRC64;
MTFLTISIIA VFVLGYACIA FESGLKVNKA AIALLMCVAC WTLFMIDPLS YVMSADPSYA
GGAAGLLSHV SGTLTHHLGA TAETLFFLMG AMTIVEIVDS HGGFNFVRDL LKTKSKRTLL
WRVAFMTFFL SAILDNLTTS IVMIMVLRKL VHDRNDRIIY ASLVILAANS GGAFSPIGDV
TTIMLWIGNK ITTAGVIKEV FVPSLVSMMV PLIIMQYSLK GELPEPQQKG SAVVADEFNE
LQRRILFTLG VGGLVFVPVF RYLTNLPPFM GILLVLGILW TVTEVFYRKA HLDEHSFSKR
VSHLLAKIDM STILFFLGIL MAVACLEEVG VLTSLGKGLD AFSQGNHYLV TGIIGVISSI
VDNVPLVAGC MGMYATAAVG DMAVDGIFWQ LLAYCAGVGG SMLIIGSAAG VVVMGLERIT
FGWYLKHVTW VAFIGYLAGM VSYGMIRSFV F
//
