ID E0S3D3_BUTPB Unreviewed; 357 AA.
AC E0S3D3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Radical SAM domain-containing protein {ECO:0000313|EMBL:ADL35915.1};
GN OrderedLocusNames=bpr_III229 {ECO:0000313|EMBL:ADL35915.1};
OS Butyrivibrio proteoclasticus (strain ATCC 51982 / DSM 14932 / B316)
OS (Clostridium proteoclasticum).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=515622 {ECO:0000313|EMBL:ADL35915.1, ECO:0000313|Proteomes:UP000001299};
RN [1] {ECO:0000313|EMBL:ADL35915.1, ECO:0000313|Proteomes:UP000001299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51982 / DSM 14932 / B316
RC {ECO:0000313|Proteomes:UP000001299};
RX PubMed=20689770; DOI=10.1371/journal.pone.0011942;
RA Kelly W.J., Leahy S.C., Altermann E., Yeoman C.J., Dunne J.C., Kong Z.,
RA Pacheco D.M., Li D., Noel S.J., Moon C.D., Cookson A.L., Attwood G.T.;
RT "The glycobiome of the rumen bacterium Butyrivibrio proteoclasticus B316(T)
RT highlights adaptation to a polysaccharide-rich environment.";
RL PLoS ONE 5:E11942-E11942(2010).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP001811; ADL35915.1; -; Genomic_DNA.
DR RefSeq; WP_013282565.1; NC_014388.1.
DR AlphaFoldDB; E0S3D3; -.
DR STRING; 515622.bpr_III229; -.
DR KEGG; bpb:bpr_III229; -.
DR eggNOG; COG0535; Bacteria.
DR HOGENOM; CLU_009273_4_1_9; -.
DR Proteomes; UP000001299; Chromosome 2.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001299};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 24..238
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 357 AA; 41062 MW; 48A889D6CC3E1320 CRC64;
MNTRNYKKSH LDIQYQVHKQ LFEQPILHQL FFEFTLRCNE HCWHCGSRCG DVKTMEMTAS
EWKQILDQVK EDFSDHLPQI NVTGGEPLLY PGFEEVMSYA HELGFKWGMT SNAILITPEV
ARMLARCGMN TISVSIDGLE ETHDSLRGLP GAYKRAMEGI QNLIDIGSFD AIMVTTVVNH
ETLGELGELF QVMNGLDIDH WRILGVEPIG RALQYPERAM TIADQRALFD FIRGKRADNM
PVSYGCSHYL GLDYEREVRD WYFTCMAGTT VASITCTGDV TGCLDIERTP SVVQGNIHER
RFSDIWRNEF KVFRRDKAAD NDTCRDCQDR NYCMGGACHT WDFENHTQRV CLAELWR
//
