ID E0SES9_DICD3 Unreviewed; 428 AA.
AC E0SES9;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=C4-dicarboxylate transport protein {ECO:0000256|HAMAP-Rule:MF_01300};
GN Name=dctA {ECO:0000256|HAMAP-Rule:MF_01300,
GN ECO:0000313|EMBL:ADM96332.1};
GN OrderedLocusNames=Dda3937_01995 {ECO:0000313|EMBL:ADM96332.1};
OS Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Dickeya.
OX NCBI_TaxID=198628 {ECO:0000313|EMBL:ADM96332.1, ECO:0000313|Proteomes:UP000006859};
RN [1] {ECO:0000313|EMBL:ADM96332.1, ECO:0000313|Proteomes:UP000006859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3937 {ECO:0000313|EMBL:ADM96332.1,
RC ECO:0000313|Proteomes:UP000006859};
RX PubMed=21217001; DOI=10.1128/JB.01513-10;
RA Glasner J.D., Yang C.H., Reverchon S., Hugouvieux-Cotte-Pattat N.,
RA Condemine G., Bohin J.P., Van Gijsegem F., Yang S., Franza T., Expert D.,
RA Plunkett G. III, San Francisco M.J., Charkowski A.O., Py B., Bell K.,
RA Rauscher L., Rodriguez-Palenzuela P., Toussaint A., Holeva M.C., He S.Y.,
RA Douet V., Boccara M., Blanco C., Toth I., Anderson B.D., Biehl B.S.,
RA Mau B., Flynn S.M., Barras F., Lindeberg M., Birch P.R., Tsuyumu S.,
RA Shi X., Hibbing M., Yap M.N., Carpentier M., Dassa E., Umehara M.,
RA Kim J.F., Rusch M., Soni P., Mayhew G.F., Fouts D.E., Gill S.R.,
RA Blattner F.R., Keen N.T., Perna N.T.;
RT "Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937.";
RL J. Bacteriol. 193:2076-2077(2011).
CC -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC succinate, fumarate, and malate from the periplasm across the membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01300}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_01300}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01300}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148,
CC ECO:0000256|HAMAP-Rule:MF_01300}.
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DR EMBL; CP002038; ADM96332.1; -; Genomic_DNA.
DR RefSeq; WP_013315821.1; NC_014500.1.
DR AlphaFoldDB; E0SES9; -.
DR STRING; 198628.Dda3937_01995; -.
DR GeneID; 9731501; -.
DR KEGG; ddd:Dda3937_01995; -.
DR PATRIC; fig|198628.6.peg.122; -.
DR eggNOG; COG1301; Bacteria.
DR HOGENOM; CLU_019375_7_0_6; -.
DR OrthoDB; 9766690at2; -.
DR Proteomes; UP000006859; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006835; P:dicarboxylic acid transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR HAMAP; MF_01300; C4_dicarb_transport; 1.
DR InterPro; IPR023954; C4_dicarb_transport.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01300};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01300};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01300};
KW Reference proteome {ECO:0000313|Proteomes:UP000006859};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|HAMAP-Rule:MF_01300};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01300};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01300};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01300}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 47..64
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 76..99
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 141..164
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 184..208
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 220..242
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 326..344
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
FT TRANSMEM 350..373
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01300"
SQ SEQUENCE 428 AA; 45233 MW; C675A8A89E5E70FF CRC64;
MKKSIFKSLY FQVLAAITIG ILLGHFYPAL GQQMQPLGDG FVKLIKMVIA PVIFCTVVTG
IAGMESMKAV GRTGAVALLY FEVVSTLALI IGLVVVNVLQ PGAGMNVDPA ALNVAAVANY
ATEAGKQGVV PFLMDVIPSS VIGAFASGNI LQVLLFAVMF GFALHRLGDK GVLIFDVIES
FSKVIFGIIN MIMRLAPLGA FGAMAFTIGK YGVGTLVQLG QLIICFYITC ILFVVLVLGS
IARATGFSIF KFIRYIREEL LIVLGTSSSE SALPRMLEKM EKLGCKKSVV GLVIPTGYSF
NLDGTSIYLT MAAVFIAQAT NSHMDIWHQI TLLVVLLLSS KGAAGVTGSG FIVLAATISA
VGHLPLAGLA LILGIDRFMS EARALTNLVG NGVATVVVAK WCKQLDSKQM NDVLSGRNDG
PAAESRPS
//
