ID E0V931_PEDHC Unreviewed; 771 AA.
AC E0V931;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN Name=8233365 {ECO:0000313|EnsemblMetazoa:PHUM003490-PA};
GN ORFNames=Phum_PHUM003490 {ECO:0000313|EMBL:EEB09887.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB09887.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB09887.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB09887.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB09887.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM003490-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM003490-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AAZO01000043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS234988; EEB09887.1; -; Genomic_DNA.
DR RefSeq; XP_002422625.1; XM_002422580.1.
DR AlphaFoldDB; E0V931; -.
DR EnsemblMetazoa; PHUM003490-RA; PHUM003490-PA; PHUM003490.
DR GeneID; 8233365; -.
DR KEGG; phu:Phum_PHUM003490; -.
DR CTD; 8233365; -.
DR VEuPathDB; VectorBase:PHUM003490; -.
DR eggNOG; KOG1056; Eukaryota.
DR HOGENOM; CLU_362620_0_0_1; -.
DR InParanoid; E0V931; -.
DR OMA; NNDESRW; -.
DR OrthoDB; 3674698at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd13953; 7tm_classC_mGluR-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF158; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 520..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..599
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 399..603
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 771 AA; 87453 MW; 1CA0E319F58445DD CRC64;
MDSCGRSRTA TTQLIEFLPQ LQINNNKSTE ENLPFKLCVI DDVGLEKEVD IQKSLEELKI
PVIGTDINTN SVSVLMDAVY NFLQEFQWER FAVIYSNSKF SSSLVKNLIK SIKKNDFCIP
WMLNVDEEDI GEELQNVVIK SKIPLVSLLT SEEHYLLFKN LPKTTNNDEE FFDKKRRWKN
IILFTDVVSR EDLKIISNNK SMRVFSIVAH PEKENNFENY FMENSILPGM EDELDLIERT
KTVQKIKKIG ERISKSLIKA VEKLCHPTEN PCTNFSTTSG REIIKNFLDE PDNSWSDNEK
SYQLVEYLFQ FSDSHVHLHK KFMKIFLLYQ VLVVITKTCP IQNVDVWKLK RFLTKPMVYS
SLSDPLTGTL ACLTLLGTLL TMVISQYFAT FAALPNGGLT SGTSVIGYVI LIGLFLLFST
NLSFLLTPLT SICAIRRFAP SLSYAMIFSG MLIKIWTYFQ QITPGKAQVT KPFTLLTYSG
IFTLLQGFIS SIWLILKPPV TEYKMGHWMC YPPNGLDCHL ILSMSYPILL LFATIVLSIR
VCSKSNNDES RWILISASLV SIIISFWAVA IGTEVWQMHR TSCTNLAAAT IILVCLYFPK
IRMHSKLKKV NKIQNNPSVH PSDITKNCSG MATNPPFPVV LGYNVGNTPP LITEEIIDSN
YINQAYSIDE SSETASTPFD IDLSSYSDLD QESPYTFSTF LEEPQSIKLV SNDTIDDPTQ
IIPSALYSID MFNTEPIAIT SDHCQPGTNE FTPPHRATSQ LYLCPQTDWV P
//
