ID E0VI38_PEDHC Unreviewed; 400 AA.
AC E0VI38;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Serine protease inhibitor, putative {ECO:0000313|EMBL:EEB13044.1, ECO:0000313|EnsemblMetazoa:PHUM220550-PA};
DE EC=2.7.11.1 {ECO:0000313|EMBL:EEB13044.1};
GN Name=8237742 {ECO:0000313|EnsemblMetazoa:PHUM220550-PA};
GN ORFNames=Phum_PHUM220550 {ECO:0000313|EMBL:EEB13044.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB13044.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB13044.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB13044.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB13044.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM220550-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM220550-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR EMBL; AAZO01002548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235184; EEB13044.1; -; Genomic_DNA.
DR RefSeq; XP_002425782.1; XM_002425737.1.
DR AlphaFoldDB; E0VI38; -.
DR EnsemblMetazoa; PHUM220550-RA; PHUM220550-PA; PHUM220550.
DR GeneID; 8237742; -.
DR KEGG; phu:Phum_PHUM220550; -.
DR CTD; 8237742; -.
DR VEuPathDB; VectorBase:PHUM220550; -.
DR eggNOG; KOG2392; Eukaryota.
DR HOGENOM; CLU_023330_0_1_1; -.
DR InParanoid; E0VI38; -.
DR OMA; GHSAYIG; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR CDD; cd19601; serpin42Da-like; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF211; ACCESSORY GLAND PROTEIN ACP76A-RELATED; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR PRINTS; PR00780; LEUSERPINII.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900};
KW Transferase {ECO:0000313|EMBL:EEB13044.1}.
FT DOMAIN 1..351
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 400 AA; 45327 MW; 6FC4F9600B43C9E7 CRC64;
MAERNIFFSP YSLQVVLAMT YSGAGGNTAK ELQQHLSFPA DKKAVESAFK KSMQKLLESK
NVTLNMANGM FVQRDYTVKP TFTKSIAESF RSEVKQLDFG DSKDSSNQIN EFVNKHTNNK
IPKLFDENAF NALTRLVLVN AIYFKGAWLH KFDPNNTYKG DFHLNEKETV KVDYMTITKK
YNYCHHEELN ASIVELKYEG DISMILVVPT AIEGLKQVEE KLVAMDLNSL LSEAYPKELN
LTMPKFKLEQ TLNLGSSLKK VGLNDMFDST KADFSGISDN RELYVSDAIQ KAYIEVNEEG
SEAAAATACH VRQRRSANFF EPEVLTLDHP FLFFIKENET DYLFFGRFGK PADVGADVVD
DDAVVVVGEK SEKMETVEKR SKSNSKSWRT FFKEDTCSGF
//
