ID E0VIH0_PEDHC Unreviewed; 1413 AA.
AC E0VIH0;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN Name=8238663 {ECO:0000313|EnsemblMetazoa:PHUM227540-PA};
GN ORFNames=Phum_PHUM227540 {ECO:0000313|EMBL:EEB13176.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB13176.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB13176.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB13176.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB13176.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM227540-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM227540-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR EMBL; AAZO01002650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235199; EEB13176.1; -; Genomic_DNA.
DR RefSeq; XP_002425914.1; XM_002425869.1.
DR STRING; 121224.E0VIH0; -.
DR EnsemblMetazoa; PHUM227540-RA; PHUM227540-PA; PHUM227540.
DR GeneID; 8238663; -.
DR KEGG; phu:Phum_PHUM227540; -.
DR CTD; 8238663; -.
DR VEuPathDB; VectorBase:PHUM227540; -.
DR eggNOG; KOG0414; Eukaryota.
DR HOGENOM; CLU_001867_3_2_1; -.
DR InParanoid; E0VIH0; -.
DR OMA; CPLEKLW; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046}.
FT DOMAIN 74..237
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1034..1191
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 1266..1394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1315..1351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1352..1366
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1413 AA; 162602 MW; 39FECFE5F3E9BEDA CRC64;
MFVRNFIIPL NRKDLLTHSS NDNFYVEEEY DVISLGEKLE FAKTALNEEG IDFIIEHFSC
MFSLLQKFKQ CSQNVKDKGW KILKKSFNIL VKSLENLFED VSCIDSELQW KMCNITKMIV
YTVIEFMKIH QDENIKQSNK VLEGKPRKKL NKVINEESDW AEEKRLILIE MHSFLLLPLK
LLWEPPVVDE DFVNLIGNFC YNCLEDPMIN SVNAKSIKET IFQILGVLIN NYLHGLSFCV
KVVQLLKTND HLVNALSYGV TYLVQECNCN SIVKEIVREV ADTDGDQLAV DISGTRNLNL
FIVQLAESVP KAIIPAIDLL ITHLNGDSYS MRICVVGVLG EIVLSILTKE NLDDNYKKMR
DEYLTCLEEH IHDVNAFVRT KVLQTWQKLC LGKAIPVSRI NRLLELVIGR LNDKSTNVKK
QAVHLIRDLL EGNPFCGQLN CLEIQNQLQQ EKKKLEQITN NYISKTDIDK WEEIKKNLLE
IISTIDQDKD SSSVDKDFDE SVDVLINSIG NYLMSGEYEK AIKMTFNLKN EFCKLYDIEI
ENCVTESLID ILHKIYTQKK TTILTISPED QEKIEKHNVV IEYLENTLEF SKLIDLALPV
ILTFLDSNVT TDVLEAINFF SSAYLFGFTK ALEGIRKMLH LIFSKESNIK SAVSNAYKDL
YFQANGNERQ KSLTTVENLS QLVLKLNFSQ LEALEEVVKE WVKTEIIDKN IVQVIFEKFS
AKNSKSENES KCWAALVLIR MIGSEEPKII KNNLSILLNE GLKNRGSKNF FIAKETCKAF
QFLVPSKEPG KNFDHSLRYP RDHEIFKVLH NLLRKGIWKT DDQYFIPMAE EAINLTFRCV
ENPDKFSCRL LHDMYNDILS KKWLKSKNEK EIKDINEIII ILLTRFISIL GQVAANYVKY
LEGPILDELK LRNQSEYEKK LRKMEENKKF NISIRKNRML EFNKVAADDM DIDEMKKRTE
NEIVKGGGGF LAKFVPLILT ICKNPGKYNN KPLQNASLIT LSKFMQVSSI FCDDNLQLLV
TICEKSQIRG RQENAIIALG ALQYRFPNNL EPWTPHMYGM LKNSNPSVRY NSILILTDLI
VNEMIKVRSH ISSLAVCVVD EDVKIARVAR HFFREYSQKG NSLYNVLPSL ISNLTQRESQ
VSPDKFKIIM KFILSLVTKE KQFEYLVEKI CQYFESATTE RQWCDLAYCL SLLSYGEKSF
KKIYENVKSF GGKMYLAEVY EAFCTIIADA GKNNQRDKGI VNEFQELVKE YRDKCCGNKI
GNLESDNRKA APVMPSKKKT KKKKYLPSDS EEEEEQEEEE EGGGGGGGAT IEDNEDIKSV
TKNLNKRKHE ETNVKKKNLI RDCKEEESRD SEDLFEKDES DEDDSGGDYS LLAGKKKKKK
RRGFDSGSPT VNGCKKKSVL LYGMNSNTPT RVR
//
