ID E0VKE8_PEDHC Unreviewed; 534 AA.
AC E0VKE8;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EEB13864.1};
GN Name=8235413 {ECO:0000313|EnsemblMetazoa:PHUM262090-PA};
GN ORFNames=Phum_PHUM262090 {ECO:0000313|EMBL:EEB13864.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB13864.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB13864.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB13864.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB13864.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM262090-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM262090-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
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DR EMBL; AAZO01003029; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235243; EEB13864.1; -; Genomic_DNA.
DR RefSeq; XP_002426602.1; XM_002426557.1.
DR AlphaFoldDB; E0VKE8; -.
DR STRING; 121224.E0VKE8; -.
DR EnsemblMetazoa; PHUM262090-RA; PHUM262090-PA; PHUM262090.
DR GeneID; 8235413; -.
DR KEGG; phu:Phum_PHUM262090; -.
DR CTD; 8235413; -.
DR VEuPathDB; VectorBase:PHUM262090; -.
DR eggNOG; KOG2806; Eukaryota.
DR HOGENOM; CLU_002833_3_1_1; -.
DR InParanoid; E0VKE8; -.
DR OMA; LDAIHVM; -.
DR OrthoDB; 2663738at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProt.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 2.170.140.10; Chitin binding domain; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR002557; Chitin-bd_dom.
DR InterPro; IPR036508; Chitin-bd_dom_sf.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF144; CHITINASE 5; 1.
DR Pfam; PF01607; CBM_14; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00494; ChtBD2; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF57625; Invertebrate chitin-binding proteins; 1.
DR PROSITE; PS50940; CHIT_BIND_II; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..534
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011412601"
FT DOMAIN 32..383
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT DOMAIN 466..523
FT /note="Chitin-binding type-2"
FT /evidence="ECO:0000259|PROSITE:PS50940"
FT REGION 419..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 61121 MW; 2B08BAB2E2E9FD9F CRC64;
MSHDKLPLFL LLVAIFMTSS SLFEKVLATG PGRITCYFSN WAIYRPNVGS YNTDDVPGNL
CTHVIYSFIG VSNVTWEILV LDDEVIAVGG WGEGGKKYSE MVSVKARRKT FIKSVVEFMN
EFNFDGFDLD WEYPGASDRG GKFSDKNNFF YFVQELRKSF DREGKGWEIT MAVPVAKFRL
NEGYHVPELC QNMNAVHVMT YDLRGNWAGF ADVHSPLYKR PHDQWGYEKL NVNDGVQLWV
DYGCPPEKLI VGIPFYGRTY KLSAGNTNFN LGTYINKEAG GGDAGPYTDA KGTLAYYEIC
WAFKNEADWI EKWDDVGLCP YAYRERNWVG YENEKSIQYK MDWIKKKGYG GSMIWSIDMD
DFQGLCGRKN PLINLIYKNM KDYVVPKSNV ITTPRPEWDR PPSTTPDIEE DITTTKKPTT
TMVTNTSSDM DFDTATEDQT TTPPYATIIT TAETTTDSNE ENYVFNSECS EDQDFIPHED
CDKYKRCVFG KPVTFTCKHN TVWVQSRQTC DYSFNADRPE CKLKKSKKIF SSTK
//
