ID E0VLI6_PEDHC Unreviewed; 875 AA.
AC E0VLI6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=WD-repeat protein, putative {ECO:0000313|EMBL:EEB14242.1, ECO:0000313|EnsemblMetazoa:PHUM288390-PA};
GN Name=8229604 {ECO:0000313|EnsemblMetazoa:PHUM288390-PA};
GN ORFNames=Phum_PHUM288390 {ECO:0000313|EMBL:EEB14242.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB14242.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB14242.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB14242.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB14242.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM288390-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM288390-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
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DR EMBL; AAZO01003348; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235271; EEB14242.1; -; Genomic_DNA.
DR RefSeq; XP_002426980.1; XM_002426935.1.
DR AlphaFoldDB; E0VLI6; -.
DR STRING; 121224.E0VLI6; -.
DR EnsemblMetazoa; PHUM288390-RA; PHUM288390-PA; PHUM288390.
DR GeneID; 8229604; -.
DR KEGG; phu:Phum_PHUM288390; -.
DR CTD; 8229604; -.
DR VEuPathDB; VectorBase:PHUM288390; -.
DR eggNOG; KOG2106; Eukaryota.
DR HOGENOM; CLU_011754_0_2_1; -.
DR InParanoid; E0VLI6; -.
DR OMA; ICCADFH; -.
DR OrthoDB; 2959353at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR CDD; cd21931; TD_EMAP-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR049813; Elp-1-like_TD.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF50; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 11.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 246..317
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 599..631
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 682..714
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 840..875
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 106..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 97009 MW; 9C0A15635A8D556A CRC64;
MAENENNNNN NSSLLMEKID DLEKKILDQG DEIICLRSTL ANVVRRLEQV EFNSKASESW
KNGNHRKFGV LRQPGFSFNS KALSKDSVKR SLSTSNSNLL QRRQAHYQST GSLHSGHSNK
SDNNNSNSAS PVPSSPSASF HSNVNTPPTY RHSVTPNSFI PSKIGDRSNL HSSKSTSNLH
NSKRWSSTGD FGINSHTSNS PLGGTFSRSS TKSLLNLFPR HGPGASTQPK SGNTDLTYNE
SEGLFRMYLR GRPIVLNIPT SLTDNYDVNE VAKPPQERLK LDWVHGYRGR DCRSNLHFLP
TGEMVYFIAA VVVLYNVEEQ SQRHYIGHTD DVKCLAVHPN KMIIATGQCA GHDSKDGKPH
IRIWNSVSLH TLAIIGLNEF EKSICCVTFS KVDGGALLCA IDESMDHTIT IWDWQKKERN
AKITENKCSV DTVIAAEFHP LDRHCIVTCG KSHIAFWILD QNGSLYKRMG IFENRDKPKF
VTCLSFTQNG DTLSGDSNGN IIVWGRGTNT ILKLIRGIHQ STVFSICVLK DGSIVTGGGK
DGKLVFLNSE FQPLDEGHIG EQYGGVRQIS ESRGSQLLVG TTRNCILIGS LGVGFSPVTI
GHTEEVWGCA AHPGLPQFLT AGFDGVIHLW DSLAHSLIWT KNIGESIQSV RFSPDGSIII
IGLTNGKWCV FDATRREILS TYQDGNEPIQ DVKFSPDNSS LALGSRDNTI YIYQALKDFT
IYHKIGRCVG HSSFITHIDW SVDSQHIRSN SGDYELLYWQ ANICRQVTQT SSMKDVEWAT
NDCTISFNTI GIWQDGMDGT DINNCAKSNN SKLLVTADDF GKLKLYTYPV IHPKSLYHTA
KGHSSHVTNV KFLNDDSRIL STGGKDTSVM QWKIS
//
