ID E0VMH3_PEDHC Unreviewed; 426 AA.
AC E0VMH3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Class A rhodopsin-like G-protein coupled receptor GPRmys, putative {ECO:0000313|EMBL:EEB14579.1, ECO:0000313|EnsemblMetazoa:PHUM309270-PA};
GN Name=8235884 {ECO:0000313|EnsemblMetazoa:PHUM309270-PA};
GN ORFNames=Phum_PHUM309270 {ECO:0000313|EMBL:EEB14579.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB14579.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB14579.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB14579.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB14579.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM309270-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM309270-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663}.
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DR EMBL; AAZO01003588; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235308; EEB14579.1; -; Genomic_DNA.
DR RefSeq; XP_002427317.1; XM_002427272.1.
DR AlphaFoldDB; E0VMH3; -.
DR EnsemblMetazoa; PHUM309270-RA; PHUM309270-PA; PHUM309270.
DR GeneID; 8235884; -.
DR KEGG; phu:Phum_PHUM309270; -.
DR CTD; 8235884; -.
DR VEuPathDB; VectorBase:PHUM309270; -.
DR eggNOG; ENOG502RFAV; Eukaryota.
DR HOGENOM; CLU_009579_24_4_1; -.
DR InParanoid; E0VMH3; -.
DR OMA; NYSACPA; -.
DR OrthoDB; 2876007at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008528; F:G protein-coupled peptide receptor activity; IEA:InterPro.
DR CDD; cd14978; 7tmA_FMRFamide_R-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019427; 7TM_GPCR_serpentine_rcpt_Srw.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR46273:SF4; AT19640P; 1.
DR PANTHER; PTHR46273; MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED; 1.
DR Pfam; PF10324; 7TM_GPCR_Srw; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EEB14579.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 90..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..388
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 426 AA; 49154 MW; 651D2FDE3953402C CRC64;
MEYSMTTTTT TTTTLPFFNP NLSYESLRKF IQSMNLTEED LYRFFKMHFP NDTIRGLILA
PREICLYDPD KYCDGTLKAF ANGYKDVHGY LSLMVCLFGT IANLINVAVL TRREMATNPI
NRILTGLAVA DVLVMLEYIP FSVYMYLIFP GQRNFPYSWA VFILFHVHFS QIIHTISICL
TLALAVWRYI AIRYPHKSIT WCTGPRCRVA IGTSFVLPLI LCIPSYFVFY IKTTRITENS
AEIYLYHLDL SDVAKENDQL LCNVTFWTYG VLIKLLPCVI LTVISIRLIK ALYEINKRNK
LLKTANSTHH NENSVERRVI LAKERTDRTT RMLVAILILF LLTELPQGIL GLLSGILGTC
FFRNCYNLFG EIMDILALVN SAINFILYCF MSRQFRQTFE KVFKINLFTE NVPRIGPPTD
MQSSYV
//
