ID E0VNU6_PEDHC Unreviewed; 935 AA.
AC E0VNU6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE SubName: Full=Exportin, putative {ECO:0000313|EMBL:EEB15052.1, ECO:0000313|EnsemblMetazoa:PHUM345850-PA};
GN Name=8231877 {ECO:0000313|EnsemblMetazoa:PHUM345850-PA};
GN ORFNames=Phum_PHUM345850 {ECO:0000313|EMBL:EEB15052.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB15052.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB15052.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB15052.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB15052.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM345850-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM345850-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; AAZO01004031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAZO01004032; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235354; EEB15052.1; -; Genomic_DNA.
DR RefSeq; XP_002427790.1; XM_002427745.1.
DR STRING; 121224.E0VNU6; -.
DR EnsemblMetazoa; PHUM345850-RA; PHUM345850-PA; PHUM345850.
DR GeneID; 8231877; -.
DR KEGG; phu:Phum_PHUM345850; -.
DR CTD; 8231877; -.
DR VEuPathDB; VectorBase:PHUM345850; -.
DR eggNOG; KOG2020; Eukaryota.
DR HOGENOM; CLU_011906_0_0_1; -.
DR InParanoid; E0VNU6; -.
DR OMA; WAFKHNN; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 570..888
FT /note="Exportin-1 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01102"
SQ SEQUENCE 935 AA; 107276 MW; 7EA1915AFA3F57AA CRC64;
MILVQILKRE WPKNWETFIT DIVGASKTNE SLCQNNMAIL KLLSEEVFDF SSGEITQTKA
KHLKDTMCSE FSQVFNLCQF VMDNSQNASL VGATLETLLR FLNWIPLGYI FETELISTLI
FKFLTVPLFR NVTLKCLTEV AGLSVNTYDT VFVALYNQTM TQLEMMLPLN TNIKEAYAQG
QDQEQIFIQN LAMFLCTFLK EHGTLLEKPE SNEVLLKGLH YLLLISEVED VEVFKICLEC
WYGLVSNLYE KHCDIYNENH YDPIGSPFMV SSRQNNFMAP RRQFYAPVLS KVRYIMISRM
ARPEEVLIVE NDNGEVVXXE TLVYLTNLDF PDTERIMTEK LQNQVQGSEW SWKNLNSLCW
AIGSISGAMQ EEDEKRFLVT VIKDLLGLCE QKKGKDNKAI IASNIMYVVG QYPRFLRAHW
KFLKTVVNKL FEFMHETHEG VQDMACDTFI KIANKCKKLF VLPQPGEVQP FIEEILAMVT
TIICDLETRQ VHTFYEAVGL MISAEVNQTV QAKLIEKYMS LPNQVWDDII SSASKNVDVL
KDMEAVKQLG GILKTNVRAC KALGHPYVTQ LGRIYLDVLN VYKVMSENIS AAIALNGESV
TKQPLIQGMR VVKKETLKLI SDWIDHSNDH VMVLQNFIPP LLDAVLLDYQ RTIIPGAREP
EVLSAMATIV HKLEGHITSE VPKIFDAVFE CTLDMINKDF EEYPEHRTNF FLLLEAVNTH
CFPALLNIPP AQFKLVLDSI IWAFKHTMRN VADTGLEILH RLLQNVEQHE QTSQSFYQTY
FTDILQHIFS VVTDSSHTPG LTLHAKILSY MFRLVECNKI TVPLAPNVTD NVTHVQKFVA
TLLKNAFGHL SDNQIKITVQ GLFNLDEDPG AFKEHLRDFL VQIREYSGED DSDLFLEERE
AILREAQREK QRKQLLVPGM RNPHEIPEEM QEMQD
//
