ID E0VPQ7_PEDHC Unreviewed; 632 AA.
AC E0VPQ7;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN Name=8233423 {ECO:0000313|EnsemblMetazoa:PHUM363240-PA};
GN ORFNames=Phum_PHUM363240 {ECO:0000313|EMBL:EEB15362.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB15362.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB15362.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB15362.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB15362.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM363240-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM363240-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAZO01004220; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235371; EEB15362.1; -; Genomic_DNA.
DR RefSeq; XP_002428100.1; XM_002428055.1.
DR AlphaFoldDB; E0VPQ7; -.
DR EnsemblMetazoa; PHUM363240-RA; PHUM363240-PA; PHUM363240.
DR GeneID; 8233423; -.
DR KEGG; phu:Phum_PHUM363240; -.
DR CTD; 8233423; -.
DR VEuPathDB; VectorBase:PHUM363240; -.
DR eggNOG; KOG4790; Eukaryota.
DR HOGENOM; CLU_025034_0_0_1; -.
DR InParanoid; E0VPQ7; -.
DR OMA; YHMLVQD; -.
DR OrthoDB; 3740296at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR PANTHER; PTHR16024:SF10; XK-RELATED PROTEIN; 1.
DR Pfam; PF09815; XK-related; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 29..51
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 103..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 507..529
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 541..561
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 567..589
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 596..621
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT REGION 255..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..380
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 71990 MW; 6C97D12DBC93E7E1 CRC64;
MEGKMDNKNG KRISIDRYSP MLTNNQKIWL LYLLPTAFCC LVYISDIATD IALVERHFAE
ERWFSGVLTI TLIYTPPFVY FILTLINPNK WPEPNKNTTK KVYWIFKQVL LLVFFPIHAM
RRFAGKLFWS TEALLSTDVE KEEALTEASK PSPAELYLLL QAFFQAAPQA LFQTYILASH
KIPHERTGVI QFLGIMTSIA SVAIAACLYM RFESQRLAGR KTPWSLKNEE SEKSGLKSKI
SLMTTIESQI TADTIADNSP TVEETEEKIK PESPKQPQLP KGVPQSAILS LPPLPPQIRA
RLIKASGDEL PEDLQKDYDD NLDGEPLNIR TSIYGFEAKS PLKERQSLEE QPFDSEQPNS
LSPAKSLPDV PPPPLPYPLD IPNDDEISEK YNNDSDDKPE DQSLMDQSNL IESKIVTASP
SAEQSPTIEK PIEEHLSREP LIDDMSTPEH VKGGNTSVKN FQPIPLPTRK WKIQGLVEDD
FLGKLIGFIW WFLYITARVL SLATLAFFYP WVFGALIFFH YFAMVGYLIN CAKAQKSSLT
FLHLGLGFVY LLCFVEIRTR FQNPNVFTLS FVIVGLVENT LSSAAWYFFA EWSSWWFLYA
FFFIITSMIL SILSMGLYFL ILKPPTQDIY TN
//
