ID   E0VR23_PEDHC            Unreviewed;       746 AA.
AC   E0VR23;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Mitotic spindle assembly checkpoint protein MAD1, putative {ECO:0000313|EMBL:EEB15829.1};
GN   Name=8237572 {ECO:0000313|EnsemblMetazoa:PHUM390840-PA};
GN   ORFNames=Phum_PHUM390840 {ECO:0000313|EMBL:EEB15829.1};
OS   Pediculus humanus subsp. corporis (Body louse).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC   Pediculus.
OX   NCBI_TaxID=121224;
RN   [1] {ECO:0000313|EMBL:EEB15829.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|EMBL:EEB15829.1};
RA   Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA   Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA   Amedeo P., Strausberg R.;
RT   "Annotation of Pediculus humanus corporis strain USDA.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEB15829.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|EMBL:EEB15829.1};
RG   The Human Body Louse Genome Consortium;
RA   Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT   "The genome of the human body louse.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:PHUM390840-PA}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM390840-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MAD1 family.
CC       {ECO:0000256|ARBA:ARBA00008029}.
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DR   EMBL; AAZO01004572; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS235442; EEB15829.1; -; Genomic_DNA.
DR   RefSeq; XP_002428567.1; XM_002428522.1.
DR   AlphaFoldDB; E0VR23; -.
DR   STRING; 121224.E0VR23; -.
DR   EnsemblMetazoa; PHUM390840-RA; PHUM390840-PA; PHUM390840.
DR   GeneID; 8237572; -.
DR   KEGG; phu:Phum_PHUM390840; -.
DR   CTD; 8237572; -.
DR   VEuPathDB; VectorBase:PHUM390840; -.
DR   eggNOG; KOG4593; Eukaryota.
DR   HOGENOM; CLU_393441_0_0_1; -.
DR   InParanoid; E0VR23; -.
DR   OMA; YKLDFMP; -.
DR   OrthoDB; 8224at2759; -.
DR   Proteomes; UP000009046; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.30.457.60; -; 1.
DR   Gene3D; 6.10.250.90; -; 1.
DR   InterPro; IPR008672; Mad1.
DR   PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR   PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR   Pfam; PF05557; MAD; 1.
DR   SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009046}.
FT   COILED          118..288
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          459..525
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          600..627
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   746 AA;  87184 MW;  E0E938727D2F0A2E CRC64;
     MSNLSSEIFL SDDKNVSSDS KVLQSALSEI HCLSENDKSE HSIDAFSSKR KIEDEFDSVV
     SPWEFRRLKA DLCESQAQRI KLEDRIEELH KKNKEAVIFF DKEKSEMKNQ LESNRVTIKT
     LEFRLNKIRK REVDYKEELN AKLQKYECMT EKLSDKIQKL EKENKELKEN TNKFECDLDN
     SKLKYHEEIN NLKSENEKLK IDNDEKNELC SSLNARLVTA SEKAKKLEDA QSQLQLAQLK
     IKALEFEQEE FKEAKNVTLA LSEKVLRVNE LEKELNEKKL QISNLKQFLH NNILLEEMVH
     DLKIKLAANE KKVNEIPGLK GQIMQLELDL DKWKSLASEF CSDVTISSLR SYIESLQQKE
     INNVLEINNL NTLISSLENK CSTTAQQLEI SKIQNQKLET IIQKLKVGVQ LLKKKTILVS
     RERDSYRQQL DLYERDLTIT DVQEQDLNTD VENRWKSRIK SLEVTLSEYQ NHIESLELQL
     KQYQTEGPSE SIDTIFKLKE EIKKLEDSNK SLRKIKDELE RKIESKALIE KTTTDSNTKI
     LHFKENPASI AEKDIQKEMD YYQKECERLR SRVKLLESGE TLNITQKVTE DIKSCNSQKV
     LELEKELQSA NLKMQRLKEV FKKTSQEFRD VSYMLLGYRI DLTSNNKLYK LYNMYSTSQL
     DYLMFQQTKN GTLEMLGTTF AESMSKFVDE YLHSGNSIPA FLSAITLELY RLNGQSDEDD
     NEEDYKRNLE SDSIVKNFNS ESMDVN
//