ID E0VSG6_PEDHC Unreviewed; 389 AA.
AC E0VSG6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN Name=8234439 {ECO:0000313|EnsemblMetazoa:PHUM418100-PA};
GN ORFNames=Phum_PHUM418100 {ECO:0000313|EMBL:EEB16322.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB16322.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16322.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB16322.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16322.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM418100-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM418100-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAZO01005127; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235750; EEB16322.1; -; Genomic_DNA.
DR RefSeq; XP_002429060.1; XM_002429015.1.
DR AlphaFoldDB; E0VSG6; -.
DR STRING; 121224.E0VSG6; -.
DR EnsemblMetazoa; PHUM418100-RA; PHUM418100-PA; PHUM418100.
DR GeneID; 8234439; -.
DR KEGG; phu:Phum_PHUM418100; -.
DR CTD; 8234439; -.
DR VEuPathDB; VectorBase:PHUM418100; -.
DR eggNOG; KOG2113; Eukaryota.
DR HOGENOM; CLU_025598_0_0_1; -.
DR InParanoid; E0VSG6; -.
DR OMA; DCGNRVC; -.
DR OrthoDB; 50983at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd22424; KH-I_MEX3_rpt2; 1.
DR CDD; cd16518; RING-HC_MEX3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047226; KH-I_MEX3_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR047227; MEX3.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23285:SF7; LD09246P1; 1.
DR PANTHER; PTHR23285; RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00117}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 338..378
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 279..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 389 AA; 40918 MW; 30C3084EA17E04F8 CRC64;
MAVVVAVVVT ITSFSLLKEK TRIRGCKIKA LRAKTNTYIK TPVRGEEPVF VVTGRKEDVA
KAKREILSAA EHFSQIRASR KTNLGGLLGG LSPPGPPANI PGQVTIQVRV PYRVVGLVVG
PKGATIKRIQ QQTHTYIVTP SRDKEPVFEV SGLPENVQVA KREIEAHIAM RTGAGTLNGT
NMADLLGAPL IEDNSELLAS LYKTGLGSLF SCLEPSDTNS TTLNSDALNM FHPTSLTSSA
SSGAFSSSGS LSSNSSSSSN GGRIGDLVSI WNSSLERDEG IGESPGFETT TTSSNIWSFP
SSASTTGITT RPSPTASASP TDSLASITGM SLGTKRDCLV CAEKEINAAL VPCGHNLFCL
DCATRLCEGT EPACPICSRT VCQAIRILS
//
