ID E0VSQ4_PEDHC Unreviewed; 1892 AA.
AC E0VSQ4;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=BEACH domain-containing protein {ECO:0000259|PROSITE:PS50197};
GN Name=8234528 {ECO:0000313|EnsemblMetazoa:PHUM422060-PA};
GN ORFNames=Phum_PHUM422060 {ECO:0000313|EMBL:EEB16410.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB16410.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16410.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB16410.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16410.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM422060-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM422060-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAZO01005168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235755; EEB16410.1; -; Genomic_DNA.
DR RefSeq; XP_002429148.1; XM_002429103.1.
DR STRING; 121224.E0VSQ4; -.
DR EnsemblMetazoa; PHUM422060-RA; PHUM422060-PA; PHUM422060.
DR GeneID; 8234528; -.
DR KEGG; phu:Phum_PHUM422060; -.
DR CTD; 8234528; -.
DR VEuPathDB; VectorBase:PHUM422060; -.
DR eggNOG; KOG1786; Eukaryota.
DR eggNOG; KOG4190; Eukaryota.
DR HOGENOM; CLU_001454_0_0_1; -.
DR InParanoid; E0VSQ4; -.
DR OMA; AYEQFTP; -.
DR OrthoDB; 5491602at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44662; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR PANTHER; PTHR44662:SF1; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 323..591
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 1596..1631
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1774..1810
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 596..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1892 AA; 214642 MW; BD25ECC4FB6311B9 CRC64;
MDSLSLVTKE LGIPKSYLNN YKSTKNRSFA LVHNDWIASL LSGSDIPDFI CHENFTDDEV
QNLFHEKENV EPWHKILINI VEKPKSHELV IPLPRSRAVH SNNEMDLSFA QLLHYISETN
FKNMWKHYYK KHARDRGFSK TRDYFRGNSF NKNKDILIEI IRRFYGCKLI LENNTSTEYF
SSFSVQSEFE PHPNILPALC AIETEENFFI LHSVNNVVTL KDCITFSPTL INTSYTKPLF
VIYQLLQILK NSHDKGLIIG NIHLDNIYIN DELFVQVIPN LEENIFRLSN TDLEVTDSSQ
NKEKEKILLF PKSITPKPFN PVSSITQEYS LEFICNKWIK KQISNFDYLM YLNQIAGRRF
GDPSCHFIMP WVSDFATRSN GTWRDLSKSK FRLNKGDRQL DLTYESALNS SQIPHHVSDV
LSEITYYVYL SRRTPRSILC KYVRSVWVPA EYPSSIQRLQ EWTPDECIPE FFYDPTVFKS
IHEDLPNLEL PYWALTPEEF IEAHRECLES KYVSERLHHW IDLTFGYKLS GSAAVKSKNV
CLHLVESHKQ LKTSGVVQLF QYPHPPRQTQ IQYFEKVPPK TLLSSSLRLP KVVTASQFDK
GGGGGSDDEG HSSGNGEDDS FGTKSSPLIF SKFMSRSKGS LLAPFQSSSN DEPRCDQQKL
GLLSGQASNS ATPINIPKDF NPSILLTSVE TNQNFFNKTF LTKSNSSVNE EKKCKLNAKQ
IIANKRIQEM QVLGCLIVEL FLFSKIRVVD VSDLEKRLEA CLYFLNHDNL PRCLRSAVSL
LLRPFKDVQN YSFITSSGLP PPSAHQLLQP LLSSFIFPFP KLFPALYSSV SNLILCSKAI
DKHKFENTQG YQVWETLNVI KVKRFYSDLE KIWDDSLSSK NNYAIDLIFP FIKELFNNPN
TSKLSIILFL NKLCRNLGPK KTNELLLETL VNLYNSSSCD NTENLYLYHK KFLLILIVRC
GLKVFLENFI SPIVEVLGKC NNFSEEEKWD NKAYNEKQDV ETDFELKSTT FEDLSLKLGN
KQKDKLKPNP EVGVFSFDHD VSPSTTTDDE ILSQTVEHLE LNLTSSDGDQ PCIEEGNLLT
SNLSHVQSPE ITIPGGHIRR NLNSEKFDVE DDMAPLQRNF FNGVDRDDFM DLPQLKAPDV
AGDSIIWLAH RLGPVLTSRH LTRNLLRVLS LCFTGKDNLE PCKFKNETNE TKLWKLSVLK
WKVVGDENVE TVLYVLGKIS EIYGEQIILL QYLPFMSELI NLSKKKFTLT LEGGIIGCLT
LLKYIVPFMN DSTLMDQLQD TILKTIIHPV IRLVSTTSFT YPSGQRGRYT LVSKLIDCIY
LISLRIGVEM TKVHIAVPAL QRIFLIFDKA HGITSSNNFQ LESELSSSSV TSPSSTVVDN
RYLEIQRDGT TTEWSVRDIP GEPITIAHVW SEESLDSIPN DCYKDQQNTV QNKALIELKH
VFDSHLAHQC YYTFLRHLGD TTMENTLKNK NFIKDLCHQH EQELSFNTYS KKKKTSSLSI
EKEQMDSVEE RDGIGSYGSN VAVVGNKIEL QTNSSTDSAS GINGLINTDV TMIICKEKEN
SGRHLRGNWL AYWEHEIGRS EKDSKFNFKQ IKLQNFTGHG NSVRMIHCLE NENSFISGSK
DKTVKLWSLR SQGDGSSTQG CQMTYNHHRK SLLSLSFIPS LRIIASCDSV IHLWDPFIGK
TISVMDNAKV AHVNVLKALN PPSCNLVAAT TDSTLKIVDA RLCSFVSEYK ISVNSVGLIR
SVCVSPDGYW IAVGQASGLL TVLDVRTGMV LSSWKGHEAE VLQLATVNDN ILMSSSLDQT
VSAWNASDGK FKFFMKGPAE PVHCLAVYNS ELITGTTANR IGVHTSIDSQ ASFSSTKLRS
DAFKGILTSM TVLPLNKLLL LGADNGNISL LC
//
