ID E0VTP8_PEDHC Unreviewed; 426 AA.
AC E0VTP8;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=NF-kappa-B-repressing factor {ECO:0008006|Google:ProtNLM};
GN Name=8230562 {ECO:0000313|EnsemblMetazoa:PHUM434940-PA};
GN ORFNames=Phum_PHUM434940 {ECO:0000313|EMBL:EEB16754.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB16754.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16754.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB16754.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16754.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM434940-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM434940-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAZO01005313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235769; EEB16754.1; -; Genomic_DNA.
DR RefSeq; XP_002429492.1; XM_002429447.1.
DR AlphaFoldDB; E0VTP8; -.
DR EnsemblMetazoa; PHUM434940-RA; PHUM434940-PA; PHUM434940.
DR GeneID; 8230562; -.
DR KEGG; phu:Phum_PHUM434940; -.
DR CTD; 8230562; -.
DR VEuPathDB; VectorBase:PHUM434940; -.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_039663_1_0_1; -.
DR InParanoid; E0VTP8; -.
DR OMA; FMLAHKD; -.
DR OrthoDB; 1380411at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR021859; XTBD.
DR PANTHER; PTHR48342; PARTNER OF XRN-2 PROTEIN 1; 1.
DR PANTHER; PTHR48342:SF1; PARTNER OF XRN-2 PROTEIN 1; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF11952; XTBD; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS51827; XTBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009046}.
FT DOMAIN 7..91
FT /note="XRN2-binding (XTBD)"
FT /evidence="ECO:0000259|PROSITE:PS51827"
FT DOMAIN 282..328
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT DOMAIN 334..398
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 99..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 48337 MW; 8777FCBEEB7E9571 CRC64;
MSTDWDIDSY KTDYENIEHW ELKKKFMLAH KDKFSEDELV SLAQVFANIE FLGCRYPDKT
MIRVAELAKG VVEEFREQRK HTLKRTLIGS EEAASAKIKG QNFLKNQEEN DSNKGKYSSY
HTSTKSKDVE EITIGDSTDE PTSSHVSKRP KYGGVKTFKI EKKCNSSSTS ELPLGNFVLF
LDADSHPISE IQRSAIINRV TPKWCFDVGP ENSKICKIYF NNTFIASGKG KTTKLSKENA
AISAISKLRE NYFAVKVKYK FFSDKIVSSS DLNAVANEEI KEDNIGRKLM KLMGWEGGGL
GSKGQGIQKP VTSNSITIQR GGLGLFKSDE TNFEVFKGKI KEHVKNWLQE DTNQDLVFSN
EFTLDERKII HEIAKQFSLK SKSYGKDRNR NLVVFKKTKP LEIVETLKKL GGSSDKYELM
YPTKKG
//
