ID E0VU69_PEDHC Unreviewed; 591 AA.
AC E0VU69;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Zinc finger protein, putative {ECO:0000313|EMBL:EEB16925.1, ECO:0000313|EnsemblMetazoa:PHUM446370-PA};
GN Name=8231202 {ECO:0000313|EnsemblMetazoa:PHUM446370-PA};
GN ORFNames=Phum_PHUM446370 {ECO:0000313|EMBL:EEB16925.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB16925.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16925.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB16925.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16925.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM446370-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM446370-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; AAZO01005449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235780; EEB16925.1; -; Genomic_DNA.
DR RefSeq; XP_002429663.1; XM_002429618.1.
DR AlphaFoldDB; E0VU69; -.
DR EnsemblMetazoa; PHUM446370-RA; PHUM446370-PA; PHUM446370.
DR GeneID; 8231202; -.
DR KEGG; phu:Phum_PHUM446370; -.
DR CTD; 8231202; -.
DR VEuPathDB; VectorBase:PHUM446370; -.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_002678_2_2_1; -.
DR InParanoid; E0VU69; -.
DR OMA; NDHHYTH; -.
DR OrthoDB; 3391810at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1800.20; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR012934; Znf_AD.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24388:SF53; COMBGAP, ISOFORM L-RELATED; 1.
DR PANTHER; PTHR24388; ZINC FINGER PROTEIN; 1.
DR Pfam; PF07776; zf-AD; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF13894; zf-C2H2_4; 2.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00868; zf-AD; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51915; ZAD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 10..85
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT DOMAIN 229..256
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 257..286
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 287..314
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 315..342
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 343..370
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 373..400
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 401..428
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 429..456
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 457..484
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 485..513
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 191..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 12
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 15
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 58
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 61
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 591 AA; 67330 MW; 2C6231E12142C38C CRC64;
MVETVNSLED LCRLCAGKID VLMGINIFDS DHRQIFKKIT VCLPIQISID DSFPKMVCVE
CACKLDLLFD FRERSILTAH LFTNMITVNN DNIIEQTISL QEEEEQQQQP VVMESNYNQD
NDDDFKIHSP KFKNDLLSSQ VCSTECENNV HESNIVLESS TDLVPEMKSN SDLILSDSKM
NDDDDVGDVD GKKDVVSDPP NVETVKNPQT VSSKKNVRLK TGGKKNESKV CMECGRQYQT
NYKLQEHMRK HTGEKPYSCS YQDCKKAFRS KIGLAQHEAN HSGQYEFSCG TCGKGFQCKS
YLVVHQRVHS DLKPYVCKQC SQRFKTKQSL LDHMNRHLGV KPFLCDICGR GFLTKGLCKS
HQKVHSGTDN RQYPCNVCRK LFVSKSYLNT HFRIHTGEKP FMCEVCGKGF LTRVDLRIHS
TMHTGEKSFV CEMCGKAFAR RDALRCHRRS HTGERPYKCE FCGQSFTQFS PMAIHKRLHT
GERPYECDVC RKTFVSKSTM ISHKKKHHST TNNEESQFQL VTVEVQRDDG NLAPEEGHQQ
QQQQQLVVID ESSPLYLTIS KRHSGTESSS SSSKINSLNS LKNENSTVSV E
//
