ID E0VVV3_PEDHC Unreviewed; 416 AA.
AC E0VVV3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Dynein axonemal assembly factor 4 {ECO:0000256|ARBA:ARBA00024430};
GN Name=8238747 {ECO:0000313|EnsemblMetazoa:PHUM467930-PA};
GN ORFNames=Phum_PHUM467930 {ECO:0000313|EMBL:EEB17509.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB17509.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17509.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB17509.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17509.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM467930-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM467930-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, neuron projection
CC {ECO:0000256|ARBA:ARBA00004487}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Dynein axonemal particle
CC {ECO:0000256|ARBA:ARBA00024190}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAZO01005683; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235815; EEB17509.1; -; Genomic_DNA.
DR RefSeq; XP_002430247.1; XM_002430202.1.
DR AlphaFoldDB; E0VVV3; -.
DR STRING; 121224.E0VVV3; -.
DR EnsemblMetazoa; PHUM467930-RA; PHUM467930-PA; PHUM467930.
DR GeneID; 8238747; -.
DR KEGG; phu:Phum_PHUM467930; -.
DR CTD; 8238747; -.
DR VEuPathDB; VectorBase:PHUM467930; -.
DR eggNOG; KOG1124; Eukaryota.
DR HOGENOM; CLU_029084_2_0_1; -.
DR InParanoid; E0VVV3; -.
DR OMA; SSANIMM; -.
DR OrthoDB; 167568at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0120293; C:dynein axonemal particle; IEA:UniProtKB-SubCell.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003341; P:cilium movement; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd06469; p23_DYX1C1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR037894; CS_DYX1C1.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46492; DYNEIN ASSEMBLY FACTOR 4, AXONEMAL; 1.
DR PANTHER; PTHR46492:SF1; DYNEIN AXONEMAL ASSEMBLY FACTOR 4; 1.
DR Pfam; PF04969; CS; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51203; CS; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Stress response {ECO:0000313|EMBL:EEB17509.1};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
FT DOMAIN 3..87
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
SQ SEQUENCE 416 AA; 47056 MW; F96B538CC6C7036D CRC64;
MPLIVKDFVW KQTEELLTIR VPLKGVSSSS VDIFTSDNYV KASYSPFLFE VFLFSNINEK
TSKCTISDNE IIFELYKIIP KMWENLTADI SKLEMLQKRK EIIEKSHVKT EEDRKLKKEK
LSALQRLSVQ QQIDQDSKMR QVIDDKRNAA RAKAMNELDD WVINNKIEEI NKPCKGPLDL
DKVIFNETDA GVEIDVEDDS IQKKVVEPIK NEMKSTNLKS KSIDVFPMPL PRNPGTITIN
FTHRDFPTPS RESQAPQEEE WLKKQVEARR ATGFVAEDLR PEECNPTWLK DKGDSFYKVG
NYLGAVSAYS HAIKLGSKMS SLYANRGAAH LGLGNLHKAL DDCSQALDLM TPHVPANLEA
RAKCHARRGA ILCRLGLPEP GVADFQAAVG LMPNDIKLQQ DLEHAKSLTK NKSTDD
//
