ID E0VW40_PEDHC Unreviewed; 340 AA.
AC E0VW40;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Replication factor C subunit, putative {ECO:0000313|EMBL:EEB17596.1, ECO:0000313|EnsemblMetazoa:PHUM473490-PA};
DE EC=2.7.7.7 {ECO:0000313|EMBL:EEB17596.1};
GN Name=8239126 {ECO:0000313|EnsemblMetazoa:PHUM473490-PA};
GN ORFNames=Phum_PHUM473490 {ECO:0000313|EMBL:EEB17596.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB17596.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17596.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB17596.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17596.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM473490-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM473490-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000256|ARBA:ARBA00005378}.
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DR EMBL; AAZO01005740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235817; EEB17596.1; -; Genomic_DNA.
DR RefSeq; XP_002430334.1; XM_002430289.1.
DR AlphaFoldDB; E0VW40; -.
DR STRING; 121224.E0VW40; -.
DR EnsemblMetazoa; PHUM473490-RA; PHUM473490-PA; PHUM473490.
DR GeneID; 8239126; -.
DR KEGG; phu:Phum_PHUM473490; -.
DR CTD; 8239126; -.
DR VEuPathDB; VectorBase:PHUM473490; -.
DR eggNOG; KOG0990; Eukaryota.
DR HOGENOM; CLU_042324_2_0_1; -.
DR InParanoid; E0VW40; -.
DR OMA; AEDNLPW; -.
DR OrthoDB; 275853at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013748; Rep_factorC_C.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF9; REPLICATION FACTOR C SUBUNIT 5; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08542; Rep_fac_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:EEB17596.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transferase {ECO:0000313|EMBL:EEB17596.1}.
FT DOMAIN 45..189
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 340 AA; 38223 MW; 7D6152CAB7BE9FCA CRC64;
MAAAIEEQPK LNMPWVEKYR PQKLDDLISQ DYIVNTIRKL ISHKQLPHLL FYGPPGTGKT
TTILACAKVL YTPAQFASMV LELNASDDRG IGTVRGAILD FASTKTMFQG GVKLIILDEA
DAMTHDAQNA LRRIMEKYTA NVRFCIICNY LGKIIPAIQS RCTKFRFAPL DSKEILPRLE
YVIEQEKIKI SDDGKQAVLT LGQGDMRKVL NILQSTFVSF SEVNEENVYT CVGHPLQCDI
FEMLQSLLND NLSDSYKKIQ TIKTLKGLAL SDIVTELHTW VHKLELPSKV VCLLLISLSD
IEYNLNNGSS ENIELGKLLS AFYKARTLSV DIAKTLEENF
//
