ID E0VWC7_PEDHC Unreviewed; 2188 AA.
AC E0VWC7;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Ran-binding protein, putative {ECO:0000313|EMBL:EEB17683.1, ECO:0000313|EnsemblMetazoa:PHUM477850-PA};
GN Name=8239418 {ECO:0000313|EnsemblMetazoa:PHUM477850-PA};
GN ORFNames=Phum_PHUM477850 {ECO:0000313|EMBL:EEB17683.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB17683.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17683.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB17683.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17683.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM477850-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM477850-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; AAZO01005788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAZO01005789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAZO01005790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235818; EEB17683.1; -; Genomic_DNA.
DR RefSeq; XP_002430421.1; XM_002430376.1.
DR STRING; 121224.E0VWC7; -.
DR EnsemblMetazoa; PHUM477850-RA; PHUM477850-PA; PHUM477850.
DR GeneID; 8239418; -.
DR KEGG; phu:Phum_PHUM477850; -.
DR CTD; 8239418; -.
DR VEuPathDB; VectorBase:PHUM477850; -.
DR eggNOG; KOG0864; Eukaryota.
DR HOGENOM; CLU_000378_0_0_1; -.
DR InParanoid; E0VWC7; -.
DR OMA; ACETPKD; -.
DR OrthoDB; 158765at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR CDD; cd13172; RanBD2_RanBP2_insect-like; 1.
DR CDD; cd13173; RanBD3_RanBP2_insect-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR045255; RanBP1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR23138:SF169; E3 SUMO-PROTEIN LIGASE RANBP2; 1.
DR PANTHER; PTHR23138; RAN BINDING PROTEIN; 1.
DR Pfam; PF00638; Ran_BP1; 2.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00160; RanBD; 2.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50196; RANBD1; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 60..93
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 1449..1585
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT DOMAIN 1938..2070
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT REGION 772..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1081..1101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1313..1335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1420..1447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1583..1643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1815..1847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1897..1943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1426..1444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1593..1610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1616..1643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1898..1913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1914..1928
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2188 AA; 244269 MW; CA30CF3A7705F6F2 CRC64;
MLHTKQDVDH HVHEIFRNLK SENERNLKCY QIAKLYYKVK DYNSAIKYIN RYILVSSNSA
AAFRLLGDCY FALNLKDKAF NSYKNSLELN ANQHDLILKI CSLIMESGCT GVSKPEYWLH
RAESIFPKSP VVFQLKEYLI KTQQSGVEST GQLDKLIASE IKVRPFDVNV RIRLLNFYLE
TNRSKLAYTN ALELEEKQLF SNNCRWYECL CNVVQAYEKD NKDLDFIFFI KKLYFLERKV
DLFMEEFQDE VKTISDCCSA LFTFDQSLHS FSKITTVPNE DTNFFKECLK HLRTQLSFHL
ATLILKKAKK EYGLWPKAQR TASPLLLQAS QSSMDLNSAW YNMWQGKKNL DKEVKMWSNC
AASRVSQAGH ILQSWCQNNE AKFLKKVFQN CGGKWQNLAY QDIFYSKEQS QGAETSHFVN
DPFFAFIPTQ IITKAELKQF DDVSQLNYTH SLHHIVWLGL SYFDSNGQLS HDFKCKTFPN
LQFTVENLSQ TGPESLNQLD VDAFVYASVL CGKAATENEV RNDRPDKLPV SISEELCTSA
QSEWWQAVYQ SYKNELSQNV SQARLKLMKG IETIRVIEQH GLDVKLIVKL AKLFQERAAG
SKNTSEITGL EGRAYLYWSA AIPLLERLEK GQKLRVFPNR LFDYKGEELT ANEIKAYLED
GRLYLGCRLM KLGRTEEAID AFQKLKGPYA AFYQGLIYEK LASEEINHLP ESITSENRSQ
HIIFLTRARD AFYLTLDRLR SPGVDFNHPL NSHLQDHLET VEKQLAVIDS DNSLNRNGDT
ESDETDIVPH RISPDVDDNM ESMINIYNAS NLLGMKSHGT PRTSKQNFLE KNSSRFEARP
SPERLDAQLR HFMMANNSGL QAVSDQLKEI KSIIQIELKD LGCITRDLLA EMKKWSDKID
GTVKKVIDAV KPDDILNFAE EDYENLNQMN LPYDSQYQSY LLNRQMTGTQ GTSTVTYGNS
LSSPISSVIT GNQMIPSPFY TGQQQAVSQL DPALLYQSLG TPSLSVIIPP QHIRSTVPSS
VQSTSHNQVH PFQIQMPPQV QLIKESPTEK LNSIAPSTQI INSFGNLSTG QISTAAPASL
KSPIQNTPLS GNVSSETTPE TVKTTEKILQ EPKMKPEINL QKKKNDVKLY GSKVEIFFLE
NNEWKKQGNG VIEIILDEDS KMGKFTLLQD NSNVPYVYDL NPNTAVKCVK FNKEAAAAAA
FVWSLKNLQS PKSETNNKAS PLDVIQKSYF KLNNDGEDEK FEMALNKVYK ILNFKKENII
GKSKAINIVK ETTNKIASIK EKSENSSEKN NNANLKTNFG GFIFNSPPII QPPSLKLNAS
NEKPKEQTKN SPFAAFSFPT TTTTKVTTTT LSVTSTTTNT NTVPSLKSIM SESPSNKNTS
SNNVNLFSSV KADPNSFKKN ENFVGFAGKD VQVFGYLNKS TSKESSKTDS NQKENDKEGG
DDDFIPTAEF TPAVDLPDLV DVKTGEENDE VLFEHRAKLL KFYSDSKEWK ERGIGNIKVL
LNQETGKVRL IMRRELVFKV CCNHYLDESM EFKPLPKNPN VLSWCAQDYS DGDLKPECFA
LKLKTQELME KFHTVIKNTQ AKMKNGKVEG MGSEEQSQKE KSKEELVPLS ELFKPKPGST
ANSGALNVSS ASSNPSFSKP STEFSFGIKN PVSTRGETLP NTTSTISVTK SSFGSATTTT
VSSVFGGTTT TTTNSNIFGG ASATASSVFG GAPVFASKNI FGAGTATTGN VFGSATPPTG
NVFGGATPPT GNVFGGAPAT KGNVFGGAPA TTGNVFGGGS TVNTFGGANN TFSTSGNIFG
SNVSNSSSTT NANVTNTGTF SMAPSSSNLS NSPNTSQPNS SNFSTSNSSN IFGGTSLSKS
NFVFGTPKTD SEKPTQFSFG SSNLKLQEKD KFSFSMVVRD DSNKNQSLSP RQEKLSESYE
KSESSPEKTE ANDQTNAATP EKVKLPTGEE DEELMYEQRC KLYRFYKDEE KDIKEWRERG
IGDVKILKHK ETRKIRLLMR RDVVLKVCLN HYVTSDIEFI KKDEKSWQWT APDFSDGEVQ
YDMFAIRFKT PEIASGFMKA LDDVKNNVAV TPIKKAGGDD ESTTETMKNF SFASLNNSQS
LDNAKQSIKE KGGTPLVKKS DDDITVVFQN QVTAEQREKA ASLHLPPNFY SYLQARDCPG
CVGCDAEDEN SILGKLSETT LKTQSNSV
//
