ID E0VX52_PEDHC Unreviewed; 645 AA.
AC E0VX52;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=SEFIR domain-containing protein {ECO:0000259|PROSITE:PS51534};
GN Name=8235993 {ECO:0000313|EnsemblMetazoa:PHUM495260-PA};
GN ORFNames=Phum_PHUM495260 {ECO:0000313|EMBL:EEB17958.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB17958.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17958.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB17958.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17958.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM495260-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM495260-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAZO01005999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235829; EEB17958.1; -; Genomic_DNA.
DR RefSeq; XP_002430696.1; XM_002430651.1.
DR AlphaFoldDB; E0VX52; -.
DR EnsemblMetazoa; PHUM495260-RA; PHUM495260-PA; PHUM495260.
DR GeneID; 8235993; -.
DR KEGG; phu:Phum_PHUM495260; -.
DR CTD; 8235993; -.
DR VEuPathDB; VectorBase:PHUM495260; -.
DR eggNOG; ENOG502S29E; Eukaryota.
DR HOGENOM; CLU_424741_0_0_1; -.
DR InParanoid; E0VX52; -.
DR OMA; CLLVYSP; -.
DR OrthoDB; 3686452at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11530; -; 1.
DR InterPro; IPR013568; SEFIR_dom.
DR PANTHER; PTHR13491; ZCCHC10 PROTEIN; 1.
DR PANTHER; PTHR13491:SF0; ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF08357; SEFIR; 1.
DR PROSITE; PS51534; SEFIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 306..444
FT /note="SEFIR"
FT /evidence="ECO:0000259|PROSITE:PS51534"
FT REGION 493..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 518..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 615..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 73597 MW; 1E5E8C34CD272488 CRC64;
MISHQSHLCE AMDMSCGTGN CDECQMKYYK LNSTDCRDLP FTQESNAQDE NLGTVYIESY
LNNFLSYKQT GFNLSFPDIK WKKMKYRFKQ EGNDMKNTCR EFQLSENSTV KNIFYDCLWS
NETYEGKTFS FEYEARKNDD VVYKKFLLKV PLAKNIDETT DLSHWEIFMY TEVNKSLFGP
TTFSLHWQPL PKRFSVNAYN VSVFSNKSGF MEIIFSTNIT CYSTKDCKYI YEKWYGNIQF
GVQPMWCNGC ECTMTKTNTF QLGGESSQPL LIGIVSITLL IPAFIYLLFL LRNYFIIKAK
KWMYPVPKLL VIFTPSISSH ANVVLALVEY LKTYCNIEPL VDELHIFHSK SRDPFRWCNE
AFQTANYVMV VASPYHKTLR VTDSVYQNTD VLLLRLLREK LASKVKKINF FVLMLPYCSE
EDIPKEAVNL KRYSFPKDIN KMLKFIHKDK SSLSCFNPNV KGGKNFYKLF GSKLKNSIAE
AQISLTKNKS EYDKMVSKTE TKAETKTKRE KNREPNETPL KPSSPSSSSS SSSSSSSSSS
SSSSSSSSSS SSSPSNLERM TTKIIFDCGV GNNNKTKEKK NVLELAEEIF SEFPGRLDNL
NLSGSGGGGG RGGGGRGEEE MESLMKNDDK WFVDNEPVNL DSLDL
//
