ID E0W2C5_PEDHC Unreviewed; 1637 AA.
AC E0W2C5;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE RecName: Full=LIM zinc-binding domain-containing protein {ECO:0000259|PROSITE:PS50023};
GN Name=8232691 {ECO:0000313|EnsemblMetazoa:PHUM589170-PA};
GN ORFNames=Phum_PHUM589170 {ECO:0000313|EMBL:EEB19781.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB19781.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB19781.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB19781.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB19781.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM589170-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM589170-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; AAZO01007178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235876; EEB19781.1; -; Genomic_DNA.
DR RefSeq; XP_002432519.1; XM_002432474.1.
DR STRING; 121224.E0W2C5; -.
DR EnsemblMetazoa; PHUM589170-RA; PHUM589170-PA; PHUM589170.
DR GeneID; 8232691; -.
DR KEGG; phu:Phum_PHUM589170; -.
DR CTD; 8232691; -.
DR VEuPathDB; VectorBase:PHUM589170; -.
DR eggNOG; KOG1704; Eukaryota.
DR HOGENOM; CLU_242973_0_0_1; -.
DR InParanoid; E0W2C5; -.
DR OMA; MEERQVQ; -.
DR OrthoDB; 6462at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM00132; LIM; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 1510..1576
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 901..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1058
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1072..1138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1166..1204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1247..1276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1382..1427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1451..1505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1572..1610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 915..942
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1031
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1086..1138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1269
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1382..1408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1577..1600
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1637 AA; 185588 MW; 03669249676D0338 CRC64;
MPGTERRHST SSEDANAPPP LRQLSQDGTE IIPTRMSKVT TPKPASNPLQ FIKTGPCDLY
KAAQEQIKKV EEIKKVEKVK DDSEDWQSEH IIERVVEVKK FELEEPDRNR RRSKTFNEMI
EERNSKGGLR KMSILSYSEE DSNDLSDLGL SSNKEKPGGG DFSNNQNGSN SFHEEREEPV
VTNTNGHNST TYDEGSSTPA TISSPEPEEY TYERAIQGYM NFANKAKVKT TNDKSGGGGG
GGGNTNGNVN FKISSMKKEP GTKIGEKLSE LEQIRLRSKS TNDISGGCSS DPSKQLPKVD
VLKRRSLFEN VDGTDSKTNE KTSKEFPVTK SIKERLSNLE KNKEEEGEEI NSKTNRSSVE
VTPLIKETIL NLEKQKSIVE CSMEKNRLST DEIPSQVSIR ERLNTLEKQQ NDKDGIITKN
KIITTEEVGP VSIKKIVADF DVATTTTPTT TTTTKEITGK LTPERDAGFK EKLETFKQTE
KIQNNHVQQE DSSKSKFEHL DIDNNNKDKS KTEMNSKIVQ NHGQEQPTTV QPDDKDYKTT
MAETVSSQKG QQPSCTDTVK GVKMAEGNFN NTAVGMGSPS DISKITNNRT SSSQTDVTNS
SQMMTMMEKS NPSDVSNTIV TQICLPDNSR PRFNISVSLN SISRTIDDDN NRMTNAYYNN
DIKTNETKEL TNKYNHHTTT TTGTTRNRVR KLTPMITNPK MSTSSLLKTV CELQIIEESE
NIDRDVCNHD GNKGKNVGDH QNMVSPSKKQ NISGDFYEGD NEVQNVLVND MITNVDKEDV
EDVGEEEFQD DLKEDSIMYT DENIDEVLGK DEDDDELETM VDDELQSESQ TEEDKIKKEL
DIFTPKEHSD VILPLKPEIM DKSISVIGNY ENVYITNQVP ELSMSPDSDI IYATMGFPLG
TRPSIEPPKE KPPPPPLELS DDESNKPELP PKPSLRRLDS TKRIKKEIRK KRSDFLGIEG
SNDDSYLEPE IYVSPPPDMM TFLQEERRLE QQLYRQSICS ESDSNHETAE SRDSGVELDR
GHVDDICWSK PDVMSEPHSR QNSETFGNTS ITSEEDEILK KEREIIEVLE KEEQWRYGNK
NSHNPEQNDI GEKLAVKLRQ LEQEKMQLER ERAEEEDRRK AEESARRQNE QRLIAKQQEL
REQEEALRFE RERLHKEQEH LERCRQNLMK QQQQQQQQQQ NPDTNVHHRS NSSSHWDTPS
NRHSLQEVPI GVPLLDVPRH SMQDVSQPPQ YQSHMSSGYR YSLPDLQQRE QPARSSRPPP
PPIPPAKPIR SLSQDPWGRE ANIRNSRIPS ADNIPLKIET STKLRHGSSV PAINLNHGAQ
QMTRSTLQAL SAAPRSRIIS NENWMQPKRK VDAPKSNYNY QHWLIQEAEH RRILEHQQKV
ASQQLQSKNS STLPLFNGQQ SGGNYGGSPP SHHTVGLPIS PPPQPVQNQK WVVSPLRIDK
PLPDAVIQTL TQRVQNRESK TPPRRRVENS GTSLPNKITQ SENVSSINPS GQQQQQQQSQ
ERMLSVSGKK KCSHCNEELG RGAAMIIESL RLFYHIDCFK CCVCHVQLGD GLMGTDVRVR
NNKLHCHNCY SSDDDRLSSE SDEEDESENS ELEIIDDETD EGNESLGRFR RDVKYPPNSR
TISILNFPTI FPHAFHL
//
