ID E0W451_PEDHC Unreviewed; 834 AA.
AC E0W451;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
GN Name=8239806 {ECO:0000313|EnsemblMetazoa:PHUM615400-PA};
GN ORFNames=Phum_PHUM615400 {ECO:0000313|EMBL:EEB20407.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB20407.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB20407.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB20407.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB20407.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM615400-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM615400-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- FUNCTION: Involved in ER-Golgi transport.
CC {ECO:0000256|ARBA:ARBA00002090}.
CC -!- SIMILARITY: Belongs to the COG3 family.
CC {ECO:0000256|ARBA:ARBA00009936}.
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DR EMBL; AAZO01007525; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235886; EEB20407.1; -; Genomic_DNA.
DR RefSeq; XP_002433145.1; XM_002433100.1.
DR AlphaFoldDB; E0W451; -.
DR STRING; 121224.E0W451; -.
DR EnsemblMetazoa; PHUM615400-RA; PHUM615400-PA; PHUM615400.
DR GeneID; 8239806; -.
DR KEGG; phu:Phum_PHUM615400; -.
DR CTD; 8239806; -.
DR VEuPathDB; VectorBase:PHUM615400; -.
DR eggNOG; KOG2604; Eukaryota.
DR HOGENOM; CLU_011639_1_1_1; -.
DR InParanoid; E0W451; -.
DR OMA; DEFELWG; -.
DR OrthoDB; 52120at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR InterPro; IPR048685; COG3_C.
DR InterPro; IPR048320; COG3_N.
DR InterPro; IPR007265; COG_su3.
DR PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR Pfam; PF20671; COG3_C; 1.
DR Pfam; PF04136; COG3_N; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 100..242
FT /note="Conserved oligomeric Golgi complex subunit 3 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04136"
FT DOMAIN 268..622
FT /note="Conserved oligomeric Golgi complex subunit 3 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20671"
FT REGION 488..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 95942 MW; BC67A51D89A6A4A3 CRC64;
MAGMTLSSKE IEKIKHKLIE WDNLKNPKAP LNEKQLLAID KIADAVKYQP FSTQIPKDES
KVETNYDSEN DNIESVQQFL KNYSEIEDKI LEEGKTVYLE YFKQLCSWRD ETDEVLVLVE
KGLQNLNILL DQYNLVSNNT NSLHNACQQI LQEQMKLSKT YEEIKHKLEY FTCLDTLQQK
LSNPALSVTS DTFYGVLDKL DACIEYINNN IKFKESPSYG AKFKYCLTKA VNMMKQYISQ
TLILAKNQVL PAVTIQQNEI SKTDATNFAL FYGRFQAYAF KIKKLIYNIE QRLDKFQDYN
ILLSDCHEIY FTQRKELMSD GVKSAIIELS NRHKGDHCTL VRSGCAFLVH ICTDEYQMFF
QFFNKPTPLL MAYLEGLCLN LYDILRPIII HVNHLETLAE LCSIFRLEML EEHVQNNPLP
LEAFGKVIWQ LMQDVQERLV FRAHLYLQSD ILNYKPSPGD LAYPEKLEMM ESIALSLQEQ
AVASMKRSES RTSLASGSSA TNQEMEKTNN ETLHSAEPFR ARTGNSPADL HGMWYPPVRR
TLVTLSRLYR CVERPIFQGL SQEALSMCIQ SIASAANTIS TQKSVLDGKL FEMKHLLILR
EQVAPFQVDF TVKEMTLDFT KVKSAAYSLL QKRNRLFSLG SNNALLEFLL EGTPTVKENT
VDSRKEVDKQ LKFSCESFIE NSTNMLISGL ISFLEKVHSF MEMAKEKNKQ QQTGHVFTLR
KQSFASPEQI GSIIQDTQRQ IKTKLSHVQR LMQLYLANKE TEAILYRPIK NNIVNKFQSL
QNIIDENGYT EEDKIIMALP THDQLLILLS TYSLNASNQS SITETETPTE KESQ
//
