ID E0WR35_9ENTR Unreviewed; 464 AA.
AC E0WR35;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Cytosine NCS1 transporter {ECO:0000313|EMBL:EFL92595.1};
GN Name=codB_1 {ECO:0000313|EMBL:EFL92595.1};
GN ORFNames=REG_0407 {ECO:0000313|EMBL:EFL92595.1};
OS Candidatus Regiella insecticola LSR1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Regiella.
OX NCBI_TaxID=663321 {ECO:0000313|EMBL:EFL92595.1, ECO:0000313|Proteomes:UP000005726};
RN [1] {ECO:0000313|EMBL:EFL92595.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSR1 {ECO:0000313|EMBL:EFL92595.1};
RX PubMed=19840097;
RA Degnan P.H., Leonardo T.E., Cass B.N., Hurwitz B., Stern D., Gibbs R.A.,
RA Richards S., Moran N.A.;
RT "Dynamics of genome evolution in facultative symbionts of aphids.";
RL Environ. Microbiol. 0:0-0(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; GL379589; EFL92595.1; -; Genomic_DNA.
DR AlphaFoldDB; E0WR35; -.
DR STRING; 663321.REG_0407; -.
DR eggNOG; COG1457; Bacteria.
DR HOGENOM; CLU_035711_0_0_6; -.
DR Proteomes; UP000005726; Miscellaneous, Scaffold Scaffold1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015209; F:cytosine transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11484; SLC-NCS1sbd_CobB-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR030191; CodB.
DR InterPro; IPR001248; Pur-cyt_permease.
DR PANTHER; PTHR30569:SF0; CYTOSINE PERMEASE; 1.
DR PANTHER; PTHR30569; CYTOSINE TRANSPORTER CODB; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005726};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 464 AA; 49664 MW; 1CBC65AB0455CCD8 CRC64;
MRYLFYSIVI LYLMPDDTQS LILDLKKYTM NKNNVTSGED YAFKPVPLNA RSNLFTVTLI
RIGIMTALAQ FMLGAMLGHA MTFGEALLAT FLGSLILEFV SLGLGIAGAR EGLSTSLLAR
WCGFGRLGSV LIGLVIAVSL LGWFGVQNAV FANGLNYAFD GQLGFAWSAA ISGMVITVLV
AFGFRALSWT AKIAVPLFFF VIAWISLILL EGHNIVALIT SAPAGTPLTL GAAATAVAGG
YIVCALTTAD ISRYCQNERH VFWMVTWSII VGEFIVNSIA ILIAHALNTD DVVSIMTQTA
GVLGLLSVIL SAVKINDVNL YSSSLAFANT VEGVTGKKWR HTWLTLGLGI IGTTLSIMGI
LEEFTRFLII LGVVFPPIAG VMLVDYYILR TSRQLFDAAR AEQKLPTEAS TPQIGWLAVF
ACVVGTLAGL GIKFGIPSLN SILVAGLVYG GLAKINPSLR SSRI
//
