ID E1B703_BOVIN Unreviewed; 883 AA.
AC E1B703;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Pre-mRNA processing factor 40 homolog B {ECO:0000313|Ensembl:ENSBTAP00000022067.6};
GN Name=PRPF40B {ECO:0000313|Ensembl:ENSBTAP00000022067.6,
GN ECO:0000313|VGNC:VGNC:33380};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000022067.6, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000022067.6, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000022067.6,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000022067.6}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000022067.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; E1B703; -.
DR Ensembl; ENSBTAT00000022067.6; ENSBTAP00000022067.6; ENSBTAG00000016589.6.
DR VEuPathDB; HostDB:ENSBTAG00000016589; -.
DR VGNC; VGNC:33380; PRPF40B.
DR eggNOG; KOG0152; Eukaryota.
DR GeneTree; ENSGT00930000150980; -.
DR HOGENOM; CLU_005825_0_0_1; -.
DR TreeFam; TF318732; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000016589; Expressed in dorsal thalamus and 108 other cell types or tissues.
DR ExpressionAtlas; E1B703; baseline and differential.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 1.10.10.440; FF domain; 4.
DR InterPro; IPR002713; FF_domain.
DR InterPro; IPR036517; FF_domain_sf.
DR InterPro; IPR039726; Prp40-like.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR11864:SF1; PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG B; 1.
DR PANTHER; PTHR11864; PRE-MRNA-PROCESSING PROTEIN PRP40; 1.
DR Pfam; PF01846; FF; 3.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00441; FF; 4.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF81698; FF domain; 5.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS51676; FF; 6.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 87..120
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 133..161
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 271..325
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 335..392
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 405..465
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 485..545
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 549..605
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 620..677
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 312..351
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 449..489
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 154..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..206
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..272
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..705
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..788
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..803
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..840
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..883
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 883 AA; 100568 MW; CA879F19E9AA6F09 CRC64;
MMPPPGIPPP FPPMGLPPMS QRPPAIPPMP PGIMPPMLPP MGAPPPLTQI PGMVPPMMPG
MLMPAVPVTA ATAPGADTAS SAVAGTGPPR ALWSEHVAPD GRIYYYNADD KQSVWEKPSV
LKSKAELLLS QCPWKEYKSD TGKPYYYNNQ SKESRWTRPK DLDDLEALVK QEAAGKQQQP
QALQPQPPQP QPDPPPVPPG PTLLPTGLLE PEPGGSEDCA VSEAAQPLEQ GFLQQPEEGP
SSSAGQHQPP QQEEEESKPE PERSGLSWSN REKAKQAFKE LLRDKAVPSN ASWEQAMKMV
VTDPRYSALP KLSEKKQAFN AYKAQREKEE KEEARLRAKE AKQTLQHFLE QHERMTSTTR
YRRAEQTFGE LEVWAVVPER DRKEVYDDVL FFLAKKEKEQ AKQLRRRNIQ ALKSILDGMS
SVNFQTTWSQ AQQYLMDNPS FAQDHQLQNM DKEDALICFE EHIRALEREE EEERERARLR
ERRQQRKNRE AFQTFLDELH ETGQLHSMST WMELYPAVST DIRFANMLGQ PGSTPLDLFK
FYVEELKARF HDEKKIIKDI LKDRGFCVEV NTAFEDFAHV ISFDKRAAAL DAGNIKLTFN
SLLEKAEARE REREKEEARR LRRREAAFRS MLRQAVPALE LGTAWEEVRE RFVCDSAFEQ
ITLESERIRL FREFLQVLET ECQHLHSKGR KHGRKGKKHH RKRSHSPSGS ESGDEELPPP
SLRPPKRRRR NPSESGSEPS SSLDSVESGG AALGGRGSPS SRLLLGSGRK RREGRRTGLR
LPQTDHGLRK AKKPKKKTKK RRHKSNSPES ETDPEEKAAK ESDEKEPEQD KDRDLRRAEL
PNRSPAFGVK KEKTGWDTSE SELSEGELER RRRTLLQQLD DHQ
//
