ID E1B8R9_BOVIN Unreviewed; 450 AA.
AC E1B8R9;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=5-phosphohydroxy-L-lysine phospho-lyase {ECO:0000313|Ensembl:ENSBTAP00000018115.5};
GN Name=PHYKPL {ECO:0000313|Ensembl:ENSBTAP00000018115.5,
GN ECO:0000313|VGNC:VGNC:55298};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000018115.5, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000018115.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000018115.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000018115.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000018115.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC ECO:0000256|RuleBase:RU003560}.
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DR RefSeq; NP_001179828.1; NM_001192899.1.
DR AlphaFoldDB; E1B8R9; -.
DR SMR; E1B8R9; -.
DR STRING; 9913.ENSBTAP00000018115; -.
DR PaxDb; 9913-ENSBTAP00000018115; -.
DR Ensembl; ENSBTAT00000018115.6; ENSBTAP00000018115.5; ENSBTAG00000013628.6.
DR GeneID; 537241; -.
DR KEGG; bta:537241; -.
DR CTD; 85007; -.
DR VEuPathDB; HostDB:ENSBTAG00000013628; -.
DR VGNC; VGNC:55298; PHYKPL.
DR eggNOG; KOG1403; Eukaryota.
DR GeneTree; ENSGT00940000159222; -.
DR HOGENOM; CLU_016922_8_0_1; -.
DR InParanoid; E1B8R9; -.
DR OMA; REGLNQH; -.
DR OrthoDB; 345661at2759; -.
DR TreeFam; TF320468; -.
DR Reactome; R-BTA-1442490; Collagen degradation.
DR Reactome; R-BTA-71064; Lysine catabolism.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000013628; Expressed in laryngeal cartilage and 104 other cell types or tissues.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:InterPro.
DR CDD; cd00610; OAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR45688:SF6; 5-PHOSPHOHYDROXY-L-LYSINE PHOSPHO-LYASE; 1.
DR PANTHER; PTHR45688; ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL; 1.
DR Pfam; PF00202; Aminotran_3; 1.
DR PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU003560};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
SQ SEQUENCE 450 AA; 49612 MW; 6D97A7AE7F0BD9F4 CRC64;
MAADQRGKAA TLALRRRLLS NSCRLFFPED PIKIVRGQGQ YMYDEQGAEY IDCINNVAHV
GHCHPLVVQA AHEQNQVLNT NSRYLHDNIV DYAQRLSETL PEKLCVFYFL NSGSEANDLA
LRLARQYTGH WDVVVLDHAY HGHLSSLIDI SPYKFRDLDG QKEWVHVAPL PDTYRGPYRE
DHPNPAVAYA SEVKRVVSSA QEKGRKIAAF FAESLPSVGG QIIPPAGYFP EVAGHIRRAG
GVFVADEIQV GFGRVGKHFW AFQLQGEDFV PDIVTMGKSI GNGHPVACVA TTQAVARAFE
ATGVEYFNTF GGSPVSCAVG LAVLDVLEKE QLQAHAACVG SFLMELLGQQ KAKHPILGDI
RGVGLFIGVD LIKDEATRMP ATEEADYVVS RLKENYILLS TDGPGRNVLK FKPPMCFSLD
NARHVVAKLD AILTDMEAKV RSCETLRLHS
//
