ID E1BB01_BOVIN Unreviewed; 218 AA.
AC E1BB01;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=MAF bZIP transcription factor K {ECO:0000313|Ensembl:ENSBTAP00000025702.2};
GN Name=MAFK {ECO:0000313|VGNC:VGNC:31142};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000025702.2, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000025702.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000025702.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000025702.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000025702.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; E1BB01; -.
DR SMR; E1BB01; -.
DR STRING; 9913.ENSBTAP00000025702; -.
DR PaxDb; 9913-ENSBTAP00000025702; -.
DR Ensembl; ENSBTAT00000025702.2; ENSBTAP00000025702.2; ENSBTAG00000019303.2.
DR VEuPathDB; HostDB:ENSBTAG00000019303; -.
DR VGNC; VGNC:31142; MAFK.
DR eggNOG; KOG4196; Eukaryota.
DR GeneTree; ENSGT00940000160044; -.
DR HOGENOM; CLU_112948_0_0_1; -.
DR InParanoid; E1BB01; -.
DR OMA; VITIDWA; -.
DR TreeFam; TF325689; -.
DR Reactome; R-BTA-9707616; Heme signaling.
DR Reactome; R-BTA-9708530; Regulation of BACH1 activity.
DR Reactome; R-BTA-983231; Factors involved in megakaryocyte development and platelet production.
DR Proteomes; UP000009136; Chromosome 25.
DR Bgee; ENSBTAG00000019303; Expressed in intramuscular adipose tissue and 107 other cell types or tissues.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd14717; bZIP_Maf_small; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR004826; bZIP_Maf.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR008917; TF_DNA-bd_sf.
DR InterPro; IPR024874; Transcription_factor_Maf_fam.
DR PANTHER; PTHR10129; TRANSCRIPTION FACTOR MAF; 1.
DR PANTHER; PTHR10129:SF26; TRANSCRIPTION FACTOR MAFK; 1.
DR Pfam; PF03131; bZIP_Maf; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF47454; A DNA-binding domain in eukaryotic transcription factors; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 112..175
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT COILED 130..171
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 218 AA; 24174 MW; 2324E64C5D734075 CRC64;
MWIADRSLPF HRAESGRARG RMGCSRLSTS GDCCRHRAAR AAPAVTATIS RWFCPGDCAQ
VMTTNPKANK ALKVKKEAGE NAAALSDDEL VSMSVRELNQ HLRGLTREEV VRLKQRRRTL
KNRGYAASCR IKRVTQKEEL ERQRVELQQE VEKLARENSS MRLELDALRS KYEALQTFAR
TVARGPVTPT KVATTSVITI VKSAEMAASA SVPFSAAS
//
