ID E1BB63_BOVIN Unreviewed; 607 AA.
AC E1BB63;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=C-type lectin domain family 4 member F {ECO:0000313|Ensembl:ENSBTAP00000005991.5};
GN Name=CLEC4F {ECO:0000313|Ensembl:ENSBTAP00000005991.5,
GN ECO:0000313|VGNC:VGNC:27433};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000005991.5, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000005991.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000005991.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000005991.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000005991.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_002691277.2; XM_002691231.4.
DR RefSeq; XP_588244.5; XM_588244.8.
DR AlphaFoldDB; E1BB63; -.
DR SMR; E1BB63; -.
DR STRING; 9913.ENSBTAP00000005991; -.
DR Ensembl; ENSBTAT00000005991.5; ENSBTAP00000005991.5; ENSBTAG00000004560.5.
DR GeneID; 511001; -.
DR KEGG; bta:511001; -.
DR CTD; 165530; -.
DR VEuPathDB; HostDB:ENSBTAG00000004560; -.
DR VGNC; VGNC:27433; CLEC4F.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT01030000234575; -.
DR HOGENOM; CLU_030099_1_0_1; -.
DR InParanoid; E1BB63; -.
DR OMA; LSFQTQM; -.
DR OrthoDB; 4633257at2759; -.
DR TreeFam; TF333341; -.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000004560; Expressed in abdominal lymph node and 51 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR CDD; cd03590; CLECT_DC-SIGN_like; 1.
DR Gene3D; 1.20.5.170; -; 7.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR033989; CD209-like_CTLD.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR45710; C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180; 1.
DR PANTHER; PTHR45710:SF8; EARLY ACTIVATION ANTIGEN CD69; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF58100; Bacterial hemolysins; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lectin {ECO:0000256|ARBA:ARBA00022734}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 483..601
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT COILED 226..260
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 331..465
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 607 AA; 68039 MW; 14B3ECDA6F17F388 CRC64;
MKEAETRADQ VHFCTENQNV SLSSQGLDPV AVVPAAPRMP RRLQATLASL GVFLVSCLVV
LFIVALQHPR PALDTSAYFQ EFLGDNHTGQ FLKERDYPYH SVRVAEFQEA VQLFKGHMEN
SSTWSVEIQL LTCRVDNVSS QIQMLGGDLE SASADIQMLK GLLKDASALS FQTQLLRSSL
EETTSKIQKL QGDLEEANGS NSQIQGSFKS SLENTSIELL VLSRGLENAN TEIQVLKAGL
ETANAEVRLA NSSLKNVNAQ IHVLRGDLDS VSDLRAHHQV LRSSLESTTA EMQRLKGSLQ
NANALNSQTQ TFVRGSLDNT SAQIQVLRSH LERAGGEIHL LKRDLENVTA QTQTASSHLE
QTDAEMRVLK TELESAIALS SKIQVLNGLL RNASQEIQTL KQGMKDAAAL QSQTQMLERS
LQEARTEIQT LRKDLGNTKT LRTTIQEQQR SLESFRTALA SQEQLQRNHN QLFQLFLQGW
KFYSGSLYYF SSAKKTWQEA EQFCVSHGAH LASVTSEEEK TFLIQFTSSV YHWIGLTDHG
TEGHWRWTDG TAFDRARSRA FWAENQPDNW QHGIGQSEDC VQMQQKWNDI SCSTLCRWIC
KKPMVQL
//
