ID E1BD32_BOVIN Unreviewed; 152 AA.
AC E1BD32;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Interleukin-1 {ECO:0000256|RuleBase:RU003753};
GN Name=IL1F10 {ECO:0000313|Ensembl:ENSBTAP00000023975.4,
GN ECO:0000313|VGNC:VGNC:52788};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000023975.4, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000023975.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000023975.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000023975.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000023975.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU003753}.
CC -!- SIMILARITY: Belongs to the IL-1 family. {ECO:0000256|ARBA:ARBA00010448,
CC ECO:0000256|RuleBase:RU003753}.
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DR RefSeq; NP_001180014.1; NM_001193085.1.
DR AlphaFoldDB; E1BD32; -.
DR SMR; E1BD32; -.
DR STRING; 9913.ENSBTAP00000023975; -.
DR PaxDb; 9913-ENSBTAP00000023975; -.
DR Ensembl; ENSBTAT00000023975.5; ENSBTAP00000023975.4; ENSBTAG00000018012.5.
DR GeneID; 615702; -.
DR KEGG; bta:615702; -.
DR CTD; 84639; -.
DR VEuPathDB; HostDB:ENSBTAG00000018012; -.
DR VGNC; VGNC:52788; IL1F10.
DR eggNOG; ENOG502SN3A; Eukaryota.
DR GeneTree; ENSGT00950000182943; -.
DR HOGENOM; CLU_095373_2_0_1; -.
DR InParanoid; E1BD32; -.
DR OMA; QFYFEQS; -.
DR OrthoDB; 4292752at2759; -.
DR TreeFam; TF300203; -.
DR Reactome; R-BTA-9007892; Interleukin-38 signaling.
DR Reactome; R-BTA-9014826; Interleukin-36 pathway.
DR Proteomes; UP000009136; Chromosome 11.
DR Bgee; ENSBTAG00000018012; Expressed in zone of skin and 8 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0005125; F:cytokine activity; IBA:GO_Central.
DR GO; GO:0005149; F:interleukin-1 receptor binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071222; P:cellular response to lipopolysaccharide; IBA:GO_Central.
DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0002437; P:inflammatory response to antigenic stimulus; IBA:GO_Central.
DR GO; GO:0010628; P:positive regulation of gene expression; IBA:GO_Central.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR000975; IL-1_fam.
DR InterPro; IPR003297; IL-1RA/IL-36.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR10078; INTERLEUKIN-1 FAMILY MEMBER; 1.
DR PANTHER; PTHR10078:SF29; INTERLEUKIN-1 FAMILY MEMBER 10; 1.
DR Pfam; PF00340; IL1; 1.
DR PRINTS; PR00264; INTERLEUKIN1.
DR PRINTS; PR01360; INTRLEUKIN1X.
DR SMART; SM00125; IL1; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Secreted {ECO:0000256|RuleBase:RU003753}.
FT REGION 126..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 152 AA; 17055 MW; 7FCB8408626D6A82 CRC64;
MCSLPMAKYY IIKDAEQKAL YMRDGQFLVG DPNADNCHAE TICILPNRGL ERTKFPIFLG
VQGGSRCLAC VETGEGPSLQ LEDVNIEDLY KGGEEATRFT FFQRSSGPAF RLEAAAWPGW
FLSGSSEPQQ PLRLTKESEP SARTEFYFEQ SR
//
