ID E1BHZ2_BOVIN Unreviewed; 406 AA.
AC E1BHZ2;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Ankyrin repeat and SOCS box containing 4 {ECO:0000313|Ensembl:ENSBTAP00000024202.6};
GN Name=ASB4 {ECO:0000313|Ensembl:ENSBTAP00000024202.6,
GN ECO:0000313|VGNC:VGNC:26197};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000024202.6, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000024202.6, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000024202.6,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000024202.6}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000024202.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; E1BHZ2; -.
DR SMR; E1BHZ2; -.
DR STRING; 9913.ENSBTAP00000024202; -.
DR PaxDb; 9913-ENSBTAP00000024202; -.
DR Ensembl; ENSBTAT00000024202.6; ENSBTAP00000024202.6; ENSBTAG00000018185.6.
DR VEuPathDB; HostDB:ENSBTAG00000018185; -.
DR VGNC; VGNC:26197; ASB4.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00940000158874; -.
DR HOGENOM; CLU_035721_1_0_1; -.
DR InParanoid; E1BHZ2; -.
DR OMA; PIQYVLK; -.
DR TreeFam; TF331836; -.
DR Reactome; R-BTA-8951664; Neddylation.
DR Reactome; R-BTA-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR Proteomes; UP000009136; Chromosome 4.
DR Bgee; ENSBTAG00000018185; Expressed in longissimus thoracis muscle and 53 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24126:SF14; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10-RELATED; 1.
DR PANTHER; PTHR24126; ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 5.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 74..106
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 106..138
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 139..171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 174..206
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 251..283
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 406 AA; 46027 MW; 2654DD38923A157A CRC64;
MDGTAAPITK SAAAKLVKRN FLEALKSNDF GKLKAILIQR QIDVDTVFEV EDENMVLASY
KQGYWLPSYK LKSSWATGLH LSVLFGHVEC LLVLLDHNAT INCRPNGKTP LHVACEMANL
DCVKILCDRG AKLNCYSLSG HTALHFCTTP NSILCAKQLV WRGANVNMKT NNQDEETPLH
TAAHFGLPEL VAFYVEHGAI VDSVNAHMET PLAIATYWAL RFKEQEYSRD HHLICRMLLD
YKAEVNARDD DFKSPLHKAA WNCDHVLMDM MLEAGAEANL MDINGCAAIQ YVLKVTSVRP
AARPEICYQL LLNHGAARIY PPQFHKVIQA CHSYPKAIEV VVNAYEHIKW NVKWKRAIPD
DDLERHWDFY HSLFTVCSNS PRTLMHLSRC AIRRTLHSRC HRISLP
//
