ID E1BIR4_BOVIN Unreviewed; 569 AA.
AC E1BIR4;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Cyclic nucleotide binding domain containing 2 {ECO:0000313|Ensembl:ENSBTAP00000003652.3};
GN Name=CNBD2 {ECO:0000313|Ensembl:ENSBTAP00000003652.3,
GN ECO:0000313|VGNC:VGNC:56181};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000003652.3, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000003652.3, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000003652.3,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000003652.3}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000003652.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; E1BIR4; -.
DR SMR; E1BIR4; -.
DR STRING; 9913.ENSBTAP00000003652; -.
DR PaxDb; 9913-ENSBTAP00000003652; -.
DR Ensembl; ENSBTAT00000003652.3; ENSBTAP00000003652.3; ENSBTAG00000002822.4.
DR VEuPathDB; HostDB:ENSBTAG00000002822; -.
DR VGNC; VGNC:56181; CNBD2.
DR eggNOG; KOG1113; Eukaryota.
DR GeneTree; ENSGT00390000003964; -.
DR HOGENOM; CLU_033437_0_0_1; -.
DR InParanoid; E1BIR4; -.
DR OMA; IMMIRVC; -.
DR TreeFam; TF326269; -.
DR Proteomes; UP000009136; Chromosome 13.
DR Bgee; ENSBTAG00000002822; Expressed in oocyte and 30 other cell types or tissues.
DR ExpressionAtlas; E1BIR4; baseline.
DR GO; GO:0030552; F:cAMP binding; IBA:GO_Central.
DR GO; GO:0007283; P:spermatogenesis; IBA:GO_Central.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR InterPro; IPR043533; CNBD1/2.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR23011:SF44; CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR23011; UNCHARACTERIZED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 102..204
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 569 AA; 66832 MW; BEFFED8FC6D71A95 CRC64;
MNRYMVSRSW QILRKKLGLY HLSMDIIMMN RVCKMFRQGL RGFREYQIIE TAHRKHPIFS
FWDVSCWGHF PPRAIQITQK QPAWRAEHEI QSLCNLLQVL DSYRNYSEPL QLLLAKVMRF
ERFGRRRVIV KKGQRGNSFY FIYLGTVAVT EDEDGSSAFL DPHPTLLQKG SCFGEMGSLS
STVRRATVVC MEETEFLVVD REDFLANKLD QEVKKDAQLR FEFFRKMDLF HSWSDETLWK
LVVLGKVEKF SYGQLISKDF IESSSIMFVC EGICEVLRLI DLESSPFYHK WIWEHLQLID
DGPPNIHLKD LSPVERFKEF QIRSYPVQDF SFLKLFHLQK AQEQEGSSFS RKIKTSGNTL
PKTFGSKIKS RCSHLIKCPM IQTKYGDLPK EAAVGAYMKI HTVEQGEILG LHQILLPESQ
HDTRPLILVS LGAEVIRIRK EKFCELLDSN TIEKLSKFSI KYPSDEDLCQ RFLKENNWNI
FRKDLVRLLV EPRWRPAFTP IQPKKKGTYN PRIVMLDLYS LDKKTKRRHP IFMAPQKYLP
PLRIVQTIIA PRYKIQELLP QYKNAGVLM
//
