ID E1BNX4_BOVIN Unreviewed; 520 AA.
AC E1BNX4;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=cAMP responsive element binding protein 3 like 1 {ECO:0000313|Ensembl:ENSBTAP00000008081.5};
GN Name=CREB3L1 {ECO:0000313|Ensembl:ENSBTAP00000008081.5,
GN ECO:0000313|VGNC:VGNC:27694};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000008081.5, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000008081.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000008081.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000008081.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000008081.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; NP_001179270.1; NM_001192341.1.
DR AlphaFoldDB; E1BNX4; -.
DR SMR; E1BNX4; -.
DR PaxDb; 9913-ENSBTAP00000008081; -.
DR Ensembl; ENSBTAT00000008081.6; ENSBTAP00000008081.5; ENSBTAG00000006143.6.
DR GeneID; 513105; -.
DR KEGG; bta:513105; -.
DR CTD; 90993; -.
DR VEuPathDB; HostDB:ENSBTAG00000006143; -.
DR VGNC; VGNC:27694; CREB3L1.
DR eggNOG; KOG0709; Eukaryota.
DR GeneTree; ENSGT00940000159848; -.
DR HOGENOM; CLU_037638_1_0_1; -.
DR OMA; SNQTTGP; -.
DR OrthoDB; 3679507at2759; -.
DR TreeFam; TF316079; -.
DR Proteomes; UP000009136; Chromosome 15.
DR Bgee; ENSBTAG00000006143; Expressed in saliva-secreting gland and 104 other cell types or tissues.
DR ExpressionAtlas; E1BNX4; baseline.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0046332; F:SMAD binding; IEA:Ensembl.
DR GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR GO; GO:1903671; P:negative regulation of sprouting angiogenesis; IEA:Ensembl.
DR GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR CDD; cd14689; bZIP_CREB3; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR PANTHER; PTHR46004; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A; 1.
DR PANTHER; PTHR46004:SF1; CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR PRINTS; PR00041; LEUZIPPRCREB.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 290..353
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 71..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 57101 MW; 84F829150E8C08F3 CRC64;
MDAVLEPFPA DRLFPGSSFL DLGDLNESDF LNNAHFPEHL DHFAENMEDF SNDLFSSFFD
DPVLDEKSPL LDMELDSPTP GIQAEHSYSL SGDSAPQSPV VPIKMEDTTQ DVEHGAWVLG
HKLCSVMVKQ EQSPELPVDP LAASSAMAAA AAMATTPLLG LSPLTRLPVP HQAPGEMTQL
PVIKAEPQEV HQFLKVTPED LLQMPPTPPS SHGSDSDGSQ SPRSLPPSSP IRPMARSSTA
ISTSPLLTAP HKLQGTSGPL LLTEEEKRTL VAEGYPIPTK LPLTKAEEKA LKRVRRKIKN
KISAQESRRK KKEYVECLEK KVETFTSENN ELWKKVETLE NANRTLLQQL QKLQTLVTSK
ISRPYKMAAT QTGTCLMVAA LCFVLVLGSL VPCLPEFSSG SQTVKEDPMA TDSVYAASQM
PSRSLLFYDE GAGSWEDGRS ALLPVEPPDG WEIKPGGPVE QRPQDHLQHD HLDSTHETSK
YLSEAWPKDV GGNSTGPDFS HPKEWFHERD LGPNTTVKLS
//
