ID E1BVC2_CHICK Unreviewed; 1237 AA.
AC E1BVC2;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 3.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Cullin associated and neddylation dissociated 2 (putative) {ECO:0000313|Ensembl:ENSGALP00010027504.1};
GN Name=CAND2 {ECO:0000313|Ensembl:ENSGALP00010027504.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010027504.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010027504.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010027504.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CAND family.
CC {ECO:0000256|ARBA:ARBA00007657}.
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DR RefSeq; XP_414452.3; XM_414452.5.
DR AlphaFoldDB; E1BVC2; -.
DR SMR; E1BVC2; -.
DR STRING; 9031.ENSGALP00000013701; -.
DR Ensembl; ENSGALT00010046151.1; ENSGALP00010027504.1; ENSGALG00010019065.1.
DR GeneID; 416121; -.
DR CTD; 23066; -.
DR VEuPathDB; HostDB:geneid_416121; -.
DR GeneTree; ENSGT00390000017740; -.
DR InParanoid; E1BVC2; -.
DR OMA; WKLRAKA; -.
DR Proteomes; UP000000539; Chromosome 12.
DR Bgee; ENSGALG00000008420; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR ExpressionAtlas; E1BVC2; baseline.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:Ensembl.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0010265; P:SCF complex assembly; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039852; CAND1/CAND2.
DR InterPro; IPR013932; TATA-bd_TIP120.
DR PANTHER; PTHR12696:SF2; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR12696; TIP120; 1.
DR Pfam; PF08623; TIP120; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:E1BVC2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1046..1208
FT /note="TATA-binding protein interacting (TIP20)"
FT /evidence="ECO:0000259|Pfam:PF08623"
SQ SEQUENCE 1237 AA; 137197 MW; 14F6602446C6A98D CRC64;
MASVSYHISS LLEKMTSTDK DFRFMATNDL MMELQKDSIK LDEDSEKKVV KMLLKLLEDK
NGEVQNLAVK CLGPLVGKVK EYQVETIVDT LCTNMLSDKE QLRDISSIGL KTVISELPPA
STGSTMTANV CKKITAQLTG AIGKQEDVSV QLEALDILSD MLSRLGGTLY SFHSSILNCL
LPQLTSPRLA VRKRAIIALG HLVLTCSGNT FSELTEHLIA ELKKNESTST TRTYIQCIAG
ISRQAGHRIG EHLEKIIPLI VQYCNVDDDE LREYCFQAFE SFVRRCPKEI DPHIPNVMSL
CLKYITFDPN YNYDNEEEEE EERMETENGE DEEQESDDEY SDDDDISWKV RRAAAKCLEA
IVSSRHDLLQ DFYKTLSPVL ISRFKEREEN VKADIFSAYI SLLKQTLPIQ SWLHASDDSG
KDDVSLTMLQ NQVPNIVKAL HKQLKDKSIK SRQGCFSLLT ELAHVLPGCL AEHIPALVPG
IVFSLSDKSN SSNMRIDALS FLHVLLCNHQ PEAFHPYIKS LLPPVVACIG DPFYKITSEA
LLVAQQLVKV IRPLDKPCTF DAKPYVKDLF PGTLKRLKAA DIDQEVKERA ISCMGQIIYS
LGDHLSTDLQ PTLKIFLERL KNEITRLTAV KALTLIASSP LKIDLRPILG EGFPILASFL
RKNQRALKLS TLAALDILVK NYSDSLKPAM VESVLTELPA LISENDMHVS QVAIVFLTTL
AKVYPSSISK ITSSVLAEIF QLVHSPLLQG GALNAIIDFF QALVLTKAAT VGYSELMKQL
TAPVYSSGPS GASAALHKQA YYSAAKCVAA LSSACPKEAP GTVNQFIQDV KSPKCSSAVK
VLAFLSLAEI GRTTNLTSAQ KELKTVILDA FASPSEEVKS AASYALGNIS VGSLKEYLPF
LLKEIESQPK RQYLLLHSLK EVISSSPADS LKPYVEDIWA LLFKHCECSE EGTRNVVAEC
LGKLTLVNPS ELLPRLKKQL SSGSPHARST VVTAVKFTIA DHPQPIDTLL KGCIGSFLKT
LQDSDLNVRR VALAMFNSAA HNKPSLIRDL LNAVLPSLYN ETKVRRELIR EVEMGPFKHT
VDDGLDVRKA AFECMYTLLE SCLDRLDIYE YLNHVEDGLK DHYDIQMLTF IMLARLSTLC
PNAVLQRLER LIEPLRATCS TKVKAGSVKQ EFEKQDELKR SAMRAVAALL TIPEVEKSPA
MAEFSSQIRS SPEMASLFES IQKDTASLPT TESMDMS
//
