ID E1BWW2_CHICK Unreviewed; 390 AA.
AC E1BWW2;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 2.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Tumor susceptibility 101 {ECO:0000313|Ensembl:ENSGALP00010036514.1};
GN Name=UEVLD {ECO:0000313|Ensembl:ENSGALP00010036514.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010036514.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010036514.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010036514.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV
CC subfamily. {ECO:0000256|ARBA:ARBA00009594}.
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DR RefSeq; NP_001264344.1; NM_001277415.1.
DR AlphaFoldDB; E1BWW2; -.
DR SMR; E1BWW2; -.
DR STRING; 9031.ENSGALP00000010193; -.
DR PaxDb; 9031-ENSGALP00000010193; -.
DR Ensembl; ENSGALT00010059754.1; ENSGALP00010036514.1; ENSGALG00010024496.1.
DR GeneID; 423082; -.
DR KEGG; gga:423082; -.
DR CTD; 7251; -.
DR VEuPathDB; HostDB:geneid_423082; -.
DR GeneTree; ENSGT00940000164122; -.
DR InParanoid; E1BWW2; -.
DR Reactome; R-GGA-917729; Endosomal Sorting Complex Required For Transport (ESCRT).
DR Proteomes; UP000000539; Chromosome 5.
DR Bgee; ENSGALG00000006312; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0000813; C:ESCRT I complex; IBA:GO_Central.
DR GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR GO; GO:0008333; P:endosome to lysosome transport; IBA:GO_Central.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.140.820; -; 1.
DR Gene3D; 6.10.250.370; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR017916; SB_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR008883; UEV_N.
DR PANTHER; PTHR23306:SF17; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; 1.
DR PANTHER; PTHR23306; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED; 1.
DR Pfam; PF05743; UEV; 1.
DR Pfam; PF09454; Vps23_core; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51312; SB; 1.
DR PROSITE; PS51322; UEV; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Proteomics identification {ECO:0007829|PeptideAtlas:E1BWW2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 390 AA; 44125 MW; 7C22B9FB26EA1A57 CRC64;
MAFSESQLKK MLAKYKYRDL TIQETNSVIS QYKDLKPVMD SYVFNDGSSR ELMSLSGTIP
VPYRGNVYNI PICLWLLDTY PFNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKYP
QSDLLELIQV MIVVFGEEPP VFSRPTVSAS YPPYQATGPP TTSYVPGMPG ISPYPTGSTA
NPSFPSYPYP AGVPFPPTTN VPYYPSQPPV TTVGPSRDGT ISEDTIRASL ISAVSDKLRW
RMKEEMDRAQ AELNALKRTE EDLKKGHQKL EEMVTRLDQE VAEVDKNIEL LKKKDEELSS
ALEKMESQSE NNDIDEVIIP TAPLYKQILN LYAEENAIED TIFYLGEALR RGVIDLDVFL
KHVRLLSRKQ FQLRALMQKA RKTAGLSDLY
//
