ID E1C593_CHICK Unreviewed; 962 AA.
AC E1C593;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|ARBA:ARBA00029784, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|ARBA:ARBA00032199, ECO:0000256|RuleBase:RU366037};
GN Name=XPOT {ECO:0000313|Ensembl:ENSGALP00010018279.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010018279.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010018279.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010018279.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|RuleBase:RU366037}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; NP_001186535.1; NM_001199606.1.
DR RefSeq; XP_015137021.1; XM_015281535.1.
DR AlphaFoldDB; E1C593; -.
DR SMR; E1C593; -.
DR STRING; 9031.ENSGALP00000015971; -.
DR PaxDb; 9031-ENSGALP00000015971; -.
DR Ensembl; ENSGALT00010031343.1; ENSGALP00010018279.1; ENSGALG00010013051.1.
DR GeneID; 417824; -.
DR KEGG; gga:417824; -.
DR CTD; 11260; -.
DR VEuPathDB; HostDB:geneid_417824; -.
DR GeneTree; ENSGT00390000007890; -.
DR InParanoid; E1C593; -.
DR OMA; HEMFLFG; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000000539; Chromosome 1.
DR Bgee; ENSGALG00000009835; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IBA:GO_Central.
DR GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Proteomics identification {ECO:0007829|PeptideAtlas:E1C593};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
SQ SEQUENCE 962 AA; 109826 MW; 32A4BFE042E36D2B CRC64;
MDEQALLGLN PNADADFRQR ALAYFEQLKI SQDAWQVCAE ALAQSIYSDD HIKFFCFQVL
EHQVKFKYSE LTEVQQQLIR ETLITWLQAQ MLNPQPEKTF IRNKAAQVFA LLFVTEYLTK
WPKFFFDILS VVDLNPRGVD MYLRILMAVD AELVDRDVVH TSEEARRNTL LKDTMREQCI
PSLVESWYQI LQNYQYNNSE LTCQCLEVVG AYVSWIDLSL IANERFINML LGHMSVEVLR
EEACDCLFEI VNKGMDPIDK TKLVESLCQV LQSAGLFSID QEDDVDFLAR FSKLVNGMGQ
ALIASWTKLI KSGDMKSAQD ALQAIEAKVS LMLQLLIHED DDISSNIIGF CYDYLHILKQ
LSALSDQQKA NVEAIMLAVM KKLTYDEEYN FENEGEDEAM FVEYRKQLKL LLDRLAQVSP
ELLLASVRRV FNTTLQNWQT TRFMEVEVAI RLLYMLAEAL PVSHGAHFSG DVTKATALQD
MMRTLVTSGV SAYQHTSVTL EFFETVVRYE KFFAVEPQHI PTVLMAFLDH RGLRHSSPKV
RSRTAYLFSR FVKSLNKQMN PFIEDVLNRI QDLLELSPPE NGYQALLSSD DQLFIYETAG
VLIVNSEYSA ERKQALMRNL LTPLMEKFKV LLEKLMMAQD EDRQMALADC LNHAVGFASR
TSKAFSNKQT VKQCGCSEVY LDCLQTFLPA LSCPLQKEVL RSGVRTFLHR MIICLEEEVL
PFIPSASEHM LKDCEAKDLQ EFIPLINQIT AKFKTQVSPF LQQMFMPLLH AIFEVLLLPA
EDNDQSAALE KQMLRRSYFA FLQTVTGSGM SEVIANQGAE NVERVLFTVI QGAVDYPDPI
AQKTCFIILS KLVELWGGKD GPVGFADFVY KHIVPACFLA PLKQTFDLAD AQTVLALSEC
AVTLKTIHLK RGPECIQYLQ QEYLPSLQVA PEIIQEFCQA LQQPDAKVFK NYLKVFFQRA
KP
//
