ID E1C795_CHICK Unreviewed; 68 AA.
AC E1C795;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Guanine nucleotide-binding protein subunit gamma {ECO:0000256|RuleBase:RU004973};
GN Name=GNG10 {ECO:0000313|Ensembl:ENSGALP00010008808.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010008808.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010008808.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010008808.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC as a modulator or transducer in various transmembrane signaling
CC systems. The beta and gamma chains are required for the GTPase
CC activity, for replacement of GDP by GTP, and for G protein-effector
CC interaction. {ECO:0000256|RuleBase:RU004973}.
CC -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma.
CC {ECO:0000256|RuleBase:RU004973}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU004973};
CC Lipid-anchor {ECO:0000256|RuleBase:RU004973}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU004973}.
CC -!- SIMILARITY: Belongs to the G protein gamma family.
CC {ECO:0000256|ARBA:ARBA00007431, ECO:0000256|RuleBase:RU004973}.
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DR RefSeq; NP_001191934.1; NM_001205005.1.
DR AlphaFoldDB; E1C795; -.
DR SMR; E1C795; -.
DR STRING; 9031.ENSGALP00000025250; -.
DR PaxDb; 9031-ENSGALP00000025250; -.
DR Ensembl; ENSGALT00010014965.1; ENSGALP00010008808.1; ENSGALG00010006277.1.
DR GeneID; 769603; -.
DR KEGG; gga:769603; -.
DR CTD; 2790; -.
DR VEuPathDB; HostDB:geneid_769603; -.
DR GeneTree; ENSGT01100000263525; -.
DR InParanoid; E1C795; -.
DR OMA; QNACKDE; -.
DR OrthoDB; 2872810at2759; -.
DR Reactome; R-GGA-1296041; Activation of G protein gated Potassium channels.
DR Reactome; R-GGA-202040; G-protein activation.
DR Reactome; R-GGA-392170; ADP signalling through P2Y purinoceptor 12.
DR Reactome; R-GGA-392451; G beta:gamma signalling through PI3Kgamma.
DR Reactome; R-GGA-4086398; Ca2+ pathway.
DR Reactome; R-GGA-416476; G alpha (q) signalling events.
DR Reactome; R-GGA-416482; G alpha (12/13) signalling events.
DR Reactome; R-GGA-418217; G beta:gamma signalling through PLC beta.
DR Reactome; R-GGA-418555; G alpha (s) signalling events.
DR Reactome; R-GGA-418592; ADP signalling through P2Y purinoceptor 1.
DR Reactome; R-GGA-418594; G alpha (i) signalling events.
DR Reactome; R-GGA-418597; G alpha (z) signalling events.
DR Reactome; R-GGA-428930; Thromboxane signalling through TP receptor.
DR Reactome; R-GGA-456926; Thrombin signalling through proteinase activated receptors (PARs).
DR Reactome; R-GGA-500657; Presynaptic function of Kainate receptors.
DR Reactome; R-GGA-6814122; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.
DR Reactome; R-GGA-8964315; G beta:gamma signalling through BTK.
DR Reactome; R-GGA-8964616; G beta:gamma signalling through CDC42.
DR Reactome; R-GGA-9009391; Extra-nuclear estrogen signaling.
DR Reactome; R-GGA-9634597; GPER1 signaling.
DR Reactome; R-GGA-997272; Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits.
DR Proteomes; UP000000539; Chromosome Z.
DR Bgee; ENSGALG00000015683; Expressed in granulocyte and 12 other cell types or tissues.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR GO; GO:0031681; F:G-protein beta-subunit binding; IBA:GO_Central.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd00068; GGL; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR001770; Gprotein-gamma.
DR PANTHER; PTHR13809:SF6; GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-10; 1.
DR PANTHER; PTHR13809; GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT; 1.
DR Pfam; PF00631; G-gamma; 1.
DR PRINTS; PR00321; GPROTEING.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
PE 1: Evidence at protein level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU004973};
KW Lipoprotein {ECO:0000256|RuleBase:RU004973};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004973};
KW Proteomics identification {ECO:0007829|PeptideAtlas:E1C795};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU004973}.
SQ SEQUENCE 68 AA; 7340 MW; 227A542E1E1CA3AE CRC64;
MSSAGSLSTM QRLVEQLKLE AAVERIKVSQ AAAELQQYCM QNACKDALLV GVPAGSNPFR
EPRSCTLL
//
