ID   E1C853_CHICK            Unreviewed;       979 AA.
AC   E1C853;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 3.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=ELKS/RAB6-interacting/CAST family member 2 {ECO:0000313|Ensembl:ENSGALP00010041339.1};
GN   Name=ERC2 {ECO:0000313|Ensembl:ENSGALP00010041339.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010041339.1, ECO:0000313|Proteomes:UP000000539};
RN   [1] {ECO:0000313|Ensembl:ENSGALP00010041339.1}
RP   IDENTIFICATION.
RC   STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010041339.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; E1C853; -.
DR   SMR; E1C853; -.
DR   STRING; 9031.ENSGALP00000008691; -.
DR   PaxDb; 9031-ENSGALP00000008691; -.
DR   Ensembl; ENSGALT00010067596.1; ENSGALP00010041339.1; ENSGALG00010027887.1.
DR   VEuPathDB; HostDB:geneid_769533; -.
DR   GeneTree; ENSGT00650000093320; -.
DR   InParanoid; E1C853; -.
DR   Proteomes; UP000000539; Chromosome 12.
DR   Bgee; ENSGALG00000005419; Expressed in brain and 2 other cell types or tissues.
DR   ExpressionAtlas; E1C853; baseline.
DR   GO; GO:0048788; C:cytoskeleton of presynaptic active zone; IBA:GO_Central.
DR   GO; GO:0098882; F:structural constituent of presynaptic active zone; IBA:GO_Central.
DR   GO; GO:0048790; P:maintenance of presynaptic active zone structure; IBA:GO_Central.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IBA:GO_Central.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IBA:GO_Central.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   InterPro; IPR019323; ELKS/CAST.
DR   PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR   PANTHER; PTHR18861:SF3; ERC PROTEIN 2; 1.
DR   Pfam; PF10174; Cast; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000539}.
SQ   SEQUENCE   979 AA;  113286 MW;  120F477868E8F172 CRC64;
     MYGSARTISN LEGSPSRSPR LPRSPRLGHR RTSSGGGGGT GKTLSMENIQ SLNAAYATSG
     PMYLSDHEGV ASTTFPKGTM TLGRATNRAV YGGRVTAMGS SPNIASAGLS HTDVLSYTDQ
     HGGLTTSSHH HHHQVPSMLR QVRDSTMLDL QAQLKELQRE NDLLRKELDI KDSKLGSSMN
     SIKTFWSPEL KKERVLRKEE AARMSVLKEQ MRVSHEENQH LQMTIQALQD ELRTQRDLNH
     LLQQESGNRG AEHFTIELTE ENFRRLQAEH DRQAKELFLL RKTLEEMELR IETQKQTLNA
     RDESIKKLLE MLQSKGLPSK GMEDDNERTR RMAEAESQVN HLEVILDQKE KENIHLREEL
     HRRTQLQPEP AKTKALQTVI EMKDTKIASL ERNIRDLEDE IQMLKTNGVL NTEDREEEIK
     QIEVYKSHSK FMKNKIDQLK QELSKKESEL LALQTKLETL SNQNSDCKQH IEVLKESLTA
     KEQRAAILQT EVDALRLRLE EKETFLNKKT KQLQDLTEEK GTLAGEIRDM KDMLEVKERK
     INVLQKKIEN LQEQLRDKDK QLTNLKDRVK SLQTDSSNTD TALATLEEAL SEKERIIERL
     KEQRERDDRE RLEEIESYKK ENKDLKEKVN ALQAELTEKE SSLIDLKEHA SSLASAGLKR
     DSKLKSLEIA IEQKKEECSK LEAQLKKQAE QLFNQMYNPM PIRNNGKQGA HEAEEEARMN
     PEFADRMKQL DKEASYYREE CGKAQAEVDR LLEILKEVEN EKNDKDKKIA ELESLTSRHM
     KDQNKKVANL KHSQQLEKKK NAQLLEEVRR REDNMTDNSQ HLQVEELMNA LEKTRQELDS
     TKARLASTQQ SLAEKEAHLA NLRIERRKQL EEILEMKQEA LLAAISEKDA NIALLELSAS
     KKKKTQEEVM ALKREKDRLV HQLKQQTQNR MKLMADNYDD DHHHYHHHHH HHHHRSPGRP
     QHSNHRPSPD QDDEEGIWA
//