ID E1EX45_GIAIA Unreviewed; 1055 AA.
AC E1EX45;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 03-MAY-2023, entry version 47.
DE SubName: Full=Importin-like protein {ECO:0000313|EMBL:EFO65225.1};
GN ORFNames=GLP15_1647 {ECO:0000313|EMBL:EFO65225.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO65225.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO65225.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO65225.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO65225.1}.
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DR EMBL; ACVC01000036; EFO65225.1; -; Genomic_DNA.
DR AlphaFoldDB; E1EX45; -.
DR STRING; 658858.E1EX45; -.
DR EnsemblProtists; EFO65225; EFO65225; GLP15_1647.
DR VEuPathDB; GiardiaDB:GLP15_1647; -.
DR OMA; YSDPMSK; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
FT DOMAIN 35..104
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1055 AA; 119412 MW; CFEBA2C011130713 CRC64;
MEALLDFSQP FNYPLFVQIV EAYQQTVDYS LKQKAADVLR QFQDSPQSSQ LCMNILSQDR
STQTPMVRFF GFSLLETFIR RSWYVIPTEQ QQELCSYIMS FAAQTLSVDD VVRRKYLTIF
TLIALYTYPS SYSTFLDDVL SMRNTSLDRI NSVTILASFF EDFRVRDELL SGQKQAIQKQ
LSSEISKILV YLMDLLRDAC TQRDMFLLCL LLKLLIATVS FCDNTIKIDQ LLPFIDSLLE
YCHQVLSFGN QEVYFLSLQA LGHIYAALKS QPDTLMLKLS TFFYSIWDVV LQNYKAKVEP
CATGSSHAPP GVDPGLSPLS YSIITLPSVS TVYTCSRQQP VLTGEALFSL SFFLRSVLTS
CLDHVEKIAS SSIPPDSIDV TICLRQVASK RIGSEKLLEL ALFKYRSVLQ LLVAILVFQK
VSFDIIDIQL IEFFSFLAKK AQSCNTSNPA FKRIELYTDI FTAVQRFTIG NIPPPIEVLV
YVDEYGNLMK RELEDSEKLN MFTTMSKTIE ATTRAIKTSV AIKDLLSDLS KQFSVSAVNS
ISWSLPAVAR SIKSPDSLII TTINHLVDLS SILVSMEHKI CIASGIVYIC SQMPLFVDTK
ESIFLVILNK MLFFTSFPNE HLQEMSVRCF ALLINNIKGS AFFESAGFRG FLRNIPQIAM
QIPSSLIIIL YESISRRISD SSSTFMDYVG PLFEMLDGVL SQCPPVTIES LSTISTLYSI
FSGICEGVAG KANGEIFASS YSHFMGRTLK LYAFIHEHIL SSSGDLNLNN IFCTVRRAIS
NFLEMLMRAS TYNHIRVWFL NTSVGTNVVL PDSNSVRSDM LVLLKAYKQL LDPVNATQQS
KIDVQFVRFA HALFERIVLL SSDADKDDLI GTYFNEMLVP VLKLLATTGF AVHADLADAF
IESVCQTFTV CNAYIRRQGS EFLHVFLEFV PPIIRAVSET NLFYKHYALC FKALTILVEM
LMMRESLEVN VLSVLFVDTI RLLNKSIISS EYALLSAWWE LLQRTNEPDM ESKVFYCISP
SITANMIGYF RNGLIERNEA IIRDLFVVLR TLLWF
//
