ID E1EYN7_GIAIA Unreviewed; 452 AA.
AC E1EYN7;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Mannose-1-phosphate guanyltransferase {ECO:0000313|EMBL:EFO64674.1};
GN ORFNames=GLP15_1503 {ECO:0000313|EMBL:EFO64674.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO64674.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO64674.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO64674.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000256|ARBA:ARBA00007274}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO64674.1}.
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DR EMBL; ACVC01000074; EFO64674.1; -; Genomic_DNA.
DR AlphaFoldDB; E1EYN7; -.
DR STRING; 658858.E1EYN7; -.
DR EnsemblProtists; EFO64674; EFO64674; GLP15_1503.
DR VEuPathDB; GiardiaDB:GLP15_1503; -.
DR OMA; LEGCIVC; -.
DR OrthoDB; 5486038at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR22572:SF15; MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE BETA; 1.
DR PANTHER; PTHR22572; SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 2.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFO64674.1}.
FT DOMAIN 15..91
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT REGION 185..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 48270 MW; 3C2995AB9505C068 CRC64;
MCVNSLDVRH YMRIVLVAEQ EWLGTAGAVV SCLWAHPELS RLAYILVMNG DVVCHYPFSS
LISTYKSRNC ACLLTHFSTR DPSQYGLLKL TREDGSSAPS LSELSDRLSL SFSSKGSELS
ESLSVGDGLL SSFSFAGSAE SAGILSEEPT DASAEGDSVA SASSMVTVRQ VMRIRDYGRI
HRSGTSIARV ATPHRPSSPA GLRVNGHRSN GARSRSGDRP EGGTCKESLG PQLDLSYGQV
SLAGYSSRHL RSLSKQVASR TSARSSSGST IRLGKVSAFI EKPCYVTVES QQDRRAGHGV
SYANAGIYVI NPALLLSFPV PCSMEQEVFP ALLARKLDVL SFYVGTERTW SDMGTIAGFI
RGCQLLNGVP AFDQILDSSA QLGSQAHGTM LKSSLRGNVT DDAVRISSGA HVTNCVIYGS
TVVPPGMHLE GCIVCSGKGL AQGKHYYNKI IP
//
